Table 2. Somatic Mutations in the PIG-A... | American Society of Hematology

Table 2.

Somatic Mutations in the PIG-A Gene of Patient MSK13 Before and After BMT

DNA Sample	Exon	bp Change	aa Change	M13 Clones Mutant/Total (%)
1973	2	16 GGA → TGA	6 gly → stop	5/36 (14)
	2	211ACC → GCC	71 thr → ala	13/36 (36)
	2	$[\begin{matrix} 211 \underset{̲}{A} CC \to \underset{̲}{G} CC \\ 251 A \underset{̲}{C} C \to A \underset{̲}{T} C \end{matrix}]$	$[\begin{matrix} 71 thr \to ala \\ 84 thr \to ile \end{matrix}]$	5/36 (14)
	6	1442 TCT → TTT	481 ser → phe	13/36 (36)
1995	6	1355insAA-dupl324-1355	Frameshift^*	19/23 (83)

DNA Sample	Exon	bp Change	aa Change	M13 Clones Mutant/Total (%)
1973	2	16 GGA → TGA	6 gly → stop	5/36 (14)
	2	211ACC → GCC	71 thr → ala	13/36 (36)
	2	$[\begin{matrix} 211 \underset{̲}{A} CC \to \underset{̲}{G} CC \\ 251 A \underset{̲}{C} C \to A \underset{̲}{T} C \end{matrix}]$	$[\begin{matrix} 71 thr \to ala \\ 84 thr \to ile \end{matrix}]$	5/36 (14)
	6	1442 TCT → TTT	481 ser → phe	13/36 (36)
1995	6	1355insAA-dupl324-1355	Frameshift^*	19/23 (83)

*Predicted stop at codon 463.