Frequency of Genotypes and Haplotypes of the VNTR in Case Patients and Controls
| . | CVD . | CHD . | DVT . | ||||||
|---|---|---|---|---|---|---|---|---|---|
| No. of Patients (%) . | No. of Controls (%) . | P* (OR) . | No. of Patients (%) . | No. of Controls (%) . | P* (OR) . | No. of Patients (%) . | No. of Controls (%) . | P* (OR) . | |
| Genotype | P = .1761† | P = .0768† | P = .3153† | ||||||
| C/C | 70 (67.3) | 76 (73.1) | .363 | 55 (54.5) | 67 (66.3) | .084 | 65 (68.4) | 58 (61.1) | .288 |
| C/B | 22 (21.2) | 9 (8.7) | .011 (2.83) | 28 (27.7) | 12 (11.9) | .005 (2.84) | 10 (10.5) | 9 (9.5) | .809 |
| C/D | 9 (8.7) | 16 (15.4) | .136 | 16 (15.8) | 17 (16.8) | .849 | 16 (16.8) | 23 (24.2) | .209 |
| B/B | 1 (1.0) | 1 (1.0) | — | 0 | 2 (2.0) | — | 0 | 2 (2.1) | — |
| D/B | 1 (1.0) | 1 (1.0) | — | 1 (1.0) | 2 (2.0) | — | 2 (2.1) | 3 (3.2) | — |
| D/D | 1 (1.0) | 1 (1.0) | — | 1 (1.0) | 1 (1.0) | — | 2 (2.1) | 0 | — |
| Haplotype (%) | P = .0439† | P = .2311† | P = .5726† | ||||||
| C | 82.2 | 85.1 | .426 | 76.2 | 80.7 | .276 | 82.1 | 77.9 | .305 |
| B | 12.0 | 5.8 | .026 (2.23) | 14.4 | 8.9 | .088 (1.71) | 6.3 | 8.4 | .432 |
| D | 5.8 | 9.1 | .191 | 9.4 | 10.4 | .739 | 11.6 | 13.7 | .537 |
| . | CVD . | CHD . | DVT . | ||||||
|---|---|---|---|---|---|---|---|---|---|
| No. of Patients (%) . | No. of Controls (%) . | P* (OR) . | No. of Patients (%) . | No. of Controls (%) . | P* (OR) . | No. of Patients (%) . | No. of Controls (%) . | P* (OR) . | |
| Genotype | P = .1761† | P = .0768† | P = .3153† | ||||||
| C/C | 70 (67.3) | 76 (73.1) | .363 | 55 (54.5) | 67 (66.3) | .084 | 65 (68.4) | 58 (61.1) | .288 |
| C/B | 22 (21.2) | 9 (8.7) | .011 (2.83) | 28 (27.7) | 12 (11.9) | .005 (2.84) | 10 (10.5) | 9 (9.5) | .809 |
| C/D | 9 (8.7) | 16 (15.4) | .136 | 16 (15.8) | 17 (16.8) | .849 | 16 (16.8) | 23 (24.2) | .209 |
| B/B | 1 (1.0) | 1 (1.0) | — | 0 | 2 (2.0) | — | 0 | 2 (2.1) | — |
| D/B | 1 (1.0) | 1 (1.0) | — | 1 (1.0) | 2 (2.0) | — | 2 (2.1) | 3 (3.2) | — |
| D/D | 1 (1.0) | 1 (1.0) | — | 1 (1.0) | 1 (1.0) | — | 2 (2.1) | 0 | — |
| Haplotype (%) | P = .0439† | P = .2311† | P = .5726† | ||||||
| C | 82.2 | 85.1 | .426 | 76.2 | 80.7 | .276 | 82.1 | 77.9 | .305 |
| B | 12.0 | 5.8 | .026 (2.23) | 14.4 | 8.9 | .088 (1.71) | 6.3 | 8.4 | .432 |
| D | 5.8 | 9.1 | .191 | 9.4 | 10.4 | .739 | 11.6 | 13.7 | .537 |
Abbreviations: CVD, cerebrovascular disease; CHD, coronary heart disease; DVT, deep venous thrombosis; OR, odds ratio.
χ2 test was used to compare the value of a particular VNTR genotype/haplotype among case patients and controls.
χ2 test was used to compare the values of the distribution of VNTR genotypes/haplotypes among case patients and controls.