Age and Sex of Subjects of Study and Prevalence of Selected Risk Factors for Arterial and Venous Thrombosis Among Case Patients and Controls
| . | CVD . | CHD . | . | DVT . | ||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Patients (n = 104) . | Controls (n = 104) . | P-150 . | Patients (n = 101) . | Controls (n = 101) . | P-150 . | Patients (n = 95) . | Controls (n = 95) . | P-150 . | ||
| Age (yr) | Age (yr) | |||||||||
| Range | 24-88 | 24-89 | .996 | 34-85 | 32-86 | .595 | Range | 19-87 | 19-87 | .984 |
| Mean ± SD | 65.8 ± 13.8 | 65.8 ± 14.5 | 62.9 ± 11.1 | 63.7 ± 10.9 | Mean ± SD | 61.0 ± 14.7 | 61.0 ± 14.7 | |||
| Male sex (%) | 51.9 | 51.9 | 1 | 73.3 | 73.3 | 1 | Male sex (%) | 56.8 | 56.8 | 1 |
| Risk factors (%) | Risk factors (%) | |||||||||
| Hypertension-151 | 46.2 | 38.5 | .262 | 49.5 | 38.6 | .119 | FV Leiden +/− | 11.6 | 4.2 | .059 |
| Current/former smoker | 29.8 | 32.7 | .654 | 51.5 | 51.5 | 1 | FII 20210 A/G | 9.5 | 1.1 | .009 |
| Hypercholesterol emia-152 | 31.7 | 26.9 | .446 | 42.6 | 36.6 | .388 | OCs | 1.0 | 0 | .316 |
| Type I or II diabetes | 35.6 | 28.6 | .299 | 37.6 | 31.7 | .375 | LA | 0 | 0 | 1 |
| Family history-153 | 52.9 | 36.6 | .018 | 61.4 | 31.7 | .001 | ||||
| . | CVD . | CHD . | . | DVT . | ||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Patients (n = 104) . | Controls (n = 104) . | P-150 . | Patients (n = 101) . | Controls (n = 101) . | P-150 . | Patients (n = 95) . | Controls (n = 95) . | P-150 . | ||
| Age (yr) | Age (yr) | |||||||||
| Range | 24-88 | 24-89 | .996 | 34-85 | 32-86 | .595 | Range | 19-87 | 19-87 | .984 |
| Mean ± SD | 65.8 ± 13.8 | 65.8 ± 14.5 | 62.9 ± 11.1 | 63.7 ± 10.9 | Mean ± SD | 61.0 ± 14.7 | 61.0 ± 14.7 | |||
| Male sex (%) | 51.9 | 51.9 | 1 | 73.3 | 73.3 | 1 | Male sex (%) | 56.8 | 56.8 | 1 |
| Risk factors (%) | Risk factors (%) | |||||||||
| Hypertension-151 | 46.2 | 38.5 | .262 | 49.5 | 38.6 | .119 | FV Leiden +/− | 11.6 | 4.2 | .059 |
| Current/former smoker | 29.8 | 32.7 | .654 | 51.5 | 51.5 | 1 | FII 20210 A/G | 9.5 | 1.1 | .009 |
| Hypercholesterol emia-152 | 31.7 | 26.9 | .446 | 42.6 | 36.6 | .388 | OCs | 1.0 | 0 | .316 |
| Type I or II diabetes | 35.6 | 28.6 | .299 | 37.6 | 31.7 | .375 | LA | 0 | 0 | 1 |
| Family history-153 | 52.9 | 36.6 | .018 | 61.4 | 31.7 | .001 | ||||
Abbreviations: CVD, cerebrovascular disease; CHD, coronary heart disease; DVT, deep venus thrombosis; FV, factor V; FII, factor II; OCs, oral contraceptives; LA, lupus anticoagulant.
Student’s t-test (for age) and the χ2 test (for all other variables) were used to compare the values for case patients and controls.
Hypertension was defined as a systolic blood pressure ≥140 mm Hg at the time of admission to the hospital.
Hypercholesterolemia was defined as a total serum cholesterol level ≥5.72 mmol/L (220 mg/dL) at the time of admission to the hospital.
Family history was defined as at least one first-degree relative who had suffered from CVD and/or CHD thromboembolic episodes.