Results Within Four Parameters of Iron Status Showing Significant Differences Between Samples Obtained Before and After a 3-Month Oral Iron Supplementation
| Parameter (unit) . | Group . | Sample A Mean (range) . | Sample B Mean (range) . | Significance of Difference (P Value) . |
|---|---|---|---|---|
| sTfR (mg/L) | Men (n = 22) | 1.90 (1.12-2.66) | 1.81 (1.21-2.48) | (.3) |
| Women (n = 43) | 2.43 (1.05-3.98) | 1.85 (1.02-2.84) | (<.00001) | |
| Subgroups (n = 65): | ||||
| Normal (n = 40) | 1.84 (1.05-2.65) | 1.77 (1.02-2.48) | (.2) | |
| Stage I (n = 8) | 2.33 (1.78-2.74) | 1.91 (1.59-2.16) | (.002) | |
| Stage II (n = 17) | 3.13 (2.75-3.98) | 1.97 (1.32-2.84) | (<.00001) | |
| Ferritin (μg/L) | Men | 67.1 (8-188) | 82.6 (22-203) | (.2) |
| Women | 26.7 (4-117) | 43.7 (17-123) | (.0004) | |
| Subgroups: | ||||
| Normal | 59.1 (23-188) | 73.8 (22-203) | (.05) | |
| Stage I | 11.9 (7-19) | 29.2 (17-38) | (.0001) | |
| Stage II | 12.2 (4-21) | 32.0 (17-66) | (<.00001) | |
| TfR-F Index | Men | 1.17 (0.56-2.33) | 1.01 (0.63-1.41) | (.1) |
| Women | 2.11 (0.76-4.73) | 1.19 (0.63-1.80) | (<.00001) | |
| Subgroups: | ||||
| Normal | 1.08 (0.56-1.72) | 0.99 (0.63-1.61) | (.1) | |
| Stage I | 2.36 (1.81-3.23) | 1.33 (1.09-1.56) | (.0001) | |
| Stage II | 3.10 (2.08-4.73) | 1.34 (0.95-1.80) | (<.00001) | |
| Transferrin | ||||
| saturation (%) | Men | 21.3 (6.4-42.8) | 22.3 (14.0-38.6) | (.3) |
| Women | 18.0 (6.9-33.2) | 22.4 (7.0-45.3) | (.03) | |
| Subgroups: | ||||
| Normal | 20.6 (8.8-42.8) | 24.6 (7.0-45.3) | (.03) | |
| Stage I | 14.9 (6.4-23.0) | 15.8 (9.5-27.7) | (.4) | |
| Stage II | 18.0 (6.9-33.2) | 20.6 (8.3-40.8) | (.2) |
| Parameter (unit) . | Group . | Sample A Mean (range) . | Sample B Mean (range) . | Significance of Difference (P Value) . |
|---|---|---|---|---|
| sTfR (mg/L) | Men (n = 22) | 1.90 (1.12-2.66) | 1.81 (1.21-2.48) | (.3) |
| Women (n = 43) | 2.43 (1.05-3.98) | 1.85 (1.02-2.84) | (<.00001) | |
| Subgroups (n = 65): | ||||
| Normal (n = 40) | 1.84 (1.05-2.65) | 1.77 (1.02-2.48) | (.2) | |
| Stage I (n = 8) | 2.33 (1.78-2.74) | 1.91 (1.59-2.16) | (.002) | |
| Stage II (n = 17) | 3.13 (2.75-3.98) | 1.97 (1.32-2.84) | (<.00001) | |
| Ferritin (μg/L) | Men | 67.1 (8-188) | 82.6 (22-203) | (.2) |
| Women | 26.7 (4-117) | 43.7 (17-123) | (.0004) | |
| Subgroups: | ||||
| Normal | 59.1 (23-188) | 73.8 (22-203) | (.05) | |
| Stage I | 11.9 (7-19) | 29.2 (17-38) | (.0001) | |
| Stage II | 12.2 (4-21) | 32.0 (17-66) | (<.00001) | |
| TfR-F Index | Men | 1.17 (0.56-2.33) | 1.01 (0.63-1.41) | (.1) |
| Women | 2.11 (0.76-4.73) | 1.19 (0.63-1.80) | (<.00001) | |
| Subgroups: | ||||
| Normal | 1.08 (0.56-1.72) | 0.99 (0.63-1.61) | (.1) | |
| Stage I | 2.36 (1.81-3.23) | 1.33 (1.09-1.56) | (.0001) | |
| Stage II | 3.10 (2.08-4.73) | 1.34 (0.95-1.80) | (<.00001) | |
| Transferrin | ||||
| saturation (%) | Men | 21.3 (6.4-42.8) | 22.3 (14.0-38.6) | (.3) |
| Women | 18.0 (6.9-33.2) | 22.4 (7.0-45.3) | (.03) | |
| Subgroups: | ||||
| Normal | 20.6 (8.8-42.8) | 24.6 (7.0-45.3) | (.03) | |
| Stage I | 14.9 (6.4-23.0) | 15.8 (9.5-27.7) | (.4) | |
| Stage II | 18.0 (6.9-33.2) | 20.6 (8.3-40.8) | (.2) |
The results in men (n = 22) and women (n = 43) are shown separately, as are the results for the separate subgroups of iron status. The P values indicate the significances of differences observed between samples obtained before and those obtained after the supplementation in each group.
Abbreviations: sTfR, serum transferrin receptor; TfR-F Index, sTfR/log ferritin; stage I, depletion of storage iron compartment; stage II, depletion of the functional iron compartment.