Table 1. Inhibition of DOX-Induced... | American Society of Hematology

Table 1.

Inhibition of DOX-Induced Apoptosis by CD40L and IL-10

Culture Conditions			No. of Apoptotic Cells: Mean % of Control (SE)
DOX (0.5 μg/mL)	L Cells	Cytokines	Daudi	Raji	BJAB	BL36	BL70
−	—	—	24 (4)	9 (11)	0 (0)	2 (0)	3 (2)
+	—	—	100^-150	100^-150	100^-150	100^-150	100^-150
+	CD40L	—	36 (14)^-151	57 (12)^-151	54 (9)^-151	52 (4)^-151	65 (15)^-151
+	CDw32	—	90 (7)	85 (10)	95 (9)	105 (10)	101 (7)
+	Cdw32+Ab89		49 (11)^-151	64 (9)^-151	57 (8)^-151	NT	77 (7)^-151
+	—	IL-10	59 (18)^-151	76 (14)	53 (11)^-151	85 (2)^-151	76 (7)^-151
+	CD40L	IL-10	33 (10)^-151	40 (7)^-151	50 (3)^-151	40 (5)^-151	47 (11)^-151

Culture Conditions			No. of Apoptotic Cells: Mean % of Control (SE)
DOX (0.5 μg/mL)	L Cells	Cytokines	Daudi	Raji	BJAB	BL36	BL70
−	—	—	24 (4)	9 (11)	0 (0)	2 (0)	3 (2)
+	—	—	100^-150	100^-150	100^-150	100^-150	100^-150
+	CD40L	—	36 (14)^-151	57 (12)^-151	54 (9)^-151	52 (4)^-151	65 (15)^-151
+	CDw32	—	90 (7)	85 (10)	95 (9)	105 (10)	101 (7)
+	Cdw32+Ab89		49 (11)^-151	64 (9)^-151	57 (8)^-151	NT	77 (7)^-151
+	—	IL-10	59 (18)^-151	76 (14)	53 (11)^-151	85 (2)^-151	76 (7)^-151
+	CD40L	IL-10	33 (10)^-151	40 (7)^-151	50 (3)^-151	40 (5)^-151	47 (11)^-151

Abbreviation: NT, not tested.

Control.

P < .05 (Student’s paired t-test) as compared with DOX-treated cells in 7 experiments.