CD4+ T-Cell Counts and Infectious Events in Autografted MM Patients
Patient No. . | No. of CD4+ T Cells/μL . | Cumulative No. of Months With CD4+ T Cells <200/μL . | Infectious Events After Second HDC-150 . | |||
---|---|---|---|---|---|---|
Before First HDC . | Day 90 After Second HDC . | Day 180 After Second HDC . | Day 360 After Second HDC . | |||
1 | 892 | 170 | 291 | 266 | 4 | VZV, CMV |
2 | 361 | 91 | 11 | 351 | 6 | VZV, CMV |
3 | 350 | 95 | 150 | 146 | 8 | HZV, CMV |
4 | 315 | 327 | 307 | 234 | 0 | HSV |
5 | 259 | 77 | 75 | 88 | 12 | Other |
6 | 369 | 168 | 148 | 160 | 12 | CMV, Other |
7 | 430 | 140 | 149 | -151 | 11/11-152 | Other |
8 | 593 | 310 | ND | -151 | 0 | CMV |
9 | 124 | 64 | 199 | -153 | 6/6-152 | |
10 | 412 | 128 | -151 | -151 | 4/4-152 | CMV |
Mean ± SD | 410.5 ± 207.5 | 157 ± 92.5 | 166.2 ± 99.8 | 207.5 ± 94.9 |
Patient No. . | No. of CD4+ T Cells/μL . | Cumulative No. of Months With CD4+ T Cells <200/μL . | Infectious Events After Second HDC-150 . | |||
---|---|---|---|---|---|---|
Before First HDC . | Day 90 After Second HDC . | Day 180 After Second HDC . | Day 360 After Second HDC . | |||
1 | 892 | 170 | 291 | 266 | 4 | VZV, CMV |
2 | 361 | 91 | 11 | 351 | 6 | VZV, CMV |
3 | 350 | 95 | 150 | 146 | 8 | HZV, CMV |
4 | 315 | 327 | 307 | 234 | 0 | HSV |
5 | 259 | 77 | 75 | 88 | 12 | Other |
6 | 369 | 168 | 148 | 160 | 12 | CMV, Other |
7 | 430 | 140 | 149 | -151 | 11/11-152 | Other |
8 | 593 | 310 | ND | -151 | 0 | CMV |
9 | 124 | 64 | 199 | -153 | 6/6-152 | |
10 | 412 | 128 | -151 | -151 | 4/4-152 | CMV |
Mean ± SD | 410.5 ± 207.5 | 157 ± 92.5 | 166.2 ± 99.8 | 207.5 ± 94.9 |
CD4+ T-cell count was monitored by flow cytometry.
Abbreviation: ND, not done.
Viral manifestation of varicella (VZV), zooster (HZV), herpes (HSV), other virus (Other), or cytomegalovirus antigen detection (CMV).
Patient died before evaluation.
CD4 count could be evaluated only during the indicated time.
Patient has not reached day 360 after HDC.