Table 1.

Degradation of TOPO IIβ in Control and RA-Treated HL-60 Cells

Hours Control 48 h RA Treatment 96 h RA Treatment
2  52 ± 18  81 ± 28  62 ± 22  
30 ± 14  69 ± 12  71 ± 25  
6  13 ± 9 44 ± 7  25 ± 5 
Hours Control 48 h RA Treatment 96 h RA Treatment
2  52 ± 18  81 ± 28  62 ± 22  
30 ± 14  69 ± 12  71 ± 25  
6  13 ± 9 44 ± 7  25 ± 5 

Cells were labeled with [35S]-L-methionine for 2 hours. Values are the percentage of [35S]-label remaining ± standard error.

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