Table 2.

Functional Properties of Variants

Kd for Heparin Pentasaccharide* (nmol/L) Rate of Reaction Xa (mmol/L−1 s−1)
α-Antithrombin 550 ± 40  1.5 × 103 
Wibble (Thr85Met) 22 ± 2    4 × 103 
Rouen-VI (Asn187Asp) 170 ± 25  ND 
Kd for Heparin Pentasaccharide* (nmol/L) Rate of Reaction Xa (mmol/L−1 s−1)
α-Antithrombin 550 ± 40  1.5 × 103 
Wibble (Thr85Met) 22 ± 2    4 × 103 
Rouen-VI (Asn187Asp) 170 ± 25  ND 

Abbreviation: ND, not determined.

*

I 0.3.

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