IL-4 Secretion by Lymphocytes From B-CLL Patients and Normal Controls
| Patient No. . | Spon (pg/mL) . | PWM (pg/mL) . | Controls . | Spon (pg/mL) . | PWM (pg/mL) . |
|---|---|---|---|---|---|
| 1 | ND | ND | 1 | ND | 0.23 |
| 2 | ND | ND | 2 | ND | 3.27 |
| 3 | ND | ND | 3 | ND | 1.02 |
| 4 | ND | ND | 4 | ND | 0.15 |
| 5 | ND | ND | 5 | ND | 2.37 |
| 6 | ND | ND | 6 | ND | 4.78 |
| 7 | ND | ND | 7 | ND | ND |
| Patient No. . | Spon (pg/mL) . | PWM (pg/mL) . | Controls . | Spon (pg/mL) . | PWM (pg/mL) . |
|---|---|---|---|---|---|
| 1 | ND | ND | 1 | ND | 0.23 |
| 2 | ND | ND | 2 | ND | 3.27 |
| 3 | ND | ND | 3 | ND | 1.02 |
| 4 | ND | ND | 4 | ND | 0.15 |
| 5 | ND | ND | 5 | ND | 2.37 |
| 6 | ND | ND | 6 | ND | 4.78 |
| 7 | ND | ND | 7 | ND | ND |
IL-4 secretion by lymphocytes from normal controls was significantly increased compared with that from the patients (P < .01).
Abbreviations: Spon, spontaneous secretion; PHA, phytohemagglutinin-stimulated secretion; PWM, pokeweed mitogen-stimulated secretion; ND, not detected.