Table 1. Comparison of Cytoplasmic IL-4... | American Society of Hematology

Table 1.

Comparison of Cytoplasmic IL-4 and IL-4R Expression in B-CLL Patients Versus Controls

Patient No.	CD19/IL-4 Unst^-150	CD3/IL-4 Unst^-150	CD19/IL-4R^-150	CD3/IL-4R^-150	Controls	CD19/IL-4 Unst^-150	CD3/IL-4 Unst^-150	CD19/IL-4R^-150	CD3/IL-4R^-150
1	30.00	21.57	97.13	2.67	1	5.14	2.17	52.97	1.06
2	21.57	26.09	42.91	3.74	2	4.71	2.96	61.47	0.83
3	28.78	13.52	28.22	0.58	3	5.35	1.82	82.53	0.63
4	18.30	11.17	11.22	1.52	4	10.13	1.67	74.76	2.48
5	53.80	5.35	70.50	6.75	5	9.89	4.18	64.85	0.78
6	21.64	2.62	56.26	3.22	6	1.45	3.83	88.37	3.29
7	14.81	7.23	69.97	3.47	7	6.76	3.36	69.13	1.33
8	6.36	2.62	83.41	6.08	8	8.16	0.41	69.63	1.76
9	17.39	3.17	20.50	5.16	9	11.93	0.96	82.16	3.70
10	11.29	2.19	96.87	7.80	10	8.32	0.93	41.55	0.98

Patient No.	CD19/IL-4 Unst^-150	CD3/IL-4 Unst^-150	CD19/IL-4R^-150	CD3/IL-4R^-150	Controls	CD19/IL-4 Unst^-150	CD3/IL-4 Unst^-150	CD19/IL-4R^-150	CD3/IL-4R^-150
1	30.00	21.57	97.13	2.67	1	5.14	2.17	52.97	1.06
2	21.57	26.09	42.91	3.74	2	4.71	2.96	61.47	0.83
3	28.78	13.52	28.22	0.58	3	5.35	1.82	82.53	0.63
4	18.30	11.17	11.22	1.52	4	10.13	1.67	74.76	2.48
5	53.80	5.35	70.50	6.75	5	9.89	4.18	64.85	0.78
6	21.64	2.62	56.26	3.22	6	1.45	3.83	88.37	3.29
7	14.81	7.23	69.97	3.47	7	6.76	3.36	69.13	1.33
8	6.36	2.62	83.41	6.08	8	8.16	0.41	69.63	1.76
9	17.39	3.17	20.50	5.16	9	11.93	0.96	82.16	3.70
10	11.29	2.19	96.87	7.80	10	8.32	0.93	41.55	0.98

Abbreviation: unst, unstimulated.

F0-150

The data are presented as a percentage of CD19 and CD3⁺cells expressing cytoplasmic IL-4 and surface IL-4R. The proportion of CD3⁺ cells expressing IL-4R in B-CLL patients was significantly higher in patients than in controls (P < .01). The proportion of CD19 and CD3⁺cells expressing cytoplasmic IL-4 was also significantly higher in B-CLL patients than in controls (P < .03 andP < .01, respectively).

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