Percentage of EBV-Positive Lymphoblastoid Cells Induced to Undergo Apoptosis by Treatment With Antisense Oligodeoxynucleotide Targeted to LMP-1
| Duration of Antisense Treatment (h) . | % Apoptotic Cells . | % AntisenseInduced Apoptosis* . | ||
|---|---|---|---|---|
| Untreated . | SS1Treated . | AntisenseTreated . | ||
| 24 | 21 | — | 65 | 56 |
| 24 | 20 | 22 | 46 | 33 (31) |
| 24 | 17 | 16 | 87 | 84 (84) |
| 30 | 35 | — | 49 | 22 |
| 30 | 47 | — | 61 | 26 |
| 48 | 48 | 39 | 70 | 42 (51) |
| Duration of Antisense Treatment (h) . | % Apoptotic Cells . | % AntisenseInduced Apoptosis* . | ||
|---|---|---|---|---|
| Untreated . | SS1Treated . | AntisenseTreated . | ||
| 24 | 21 | — | 65 | 56 |
| 24 | 20 | 22 | 46 | 33 (31) |
| 24 | 17 | 16 | 87 | 84 (84) |
| 30 | 35 | — | 49 | 22 |
| 30 | 47 | — | 61 | 26 |
| 48 | 48 | 39 | 70 | 42 (51) |
*The percentage antisense-induced apoptosis is calculated relative to untreated controls and scrambled oligodeoxynucleotide (SS1)-treated cells (value shown in parentheses).