Receptor Specificity, Transcriptional Activation Activity After Binding a Particular Receptor, and Molecular Weights of the Retinoids Used
| Retinoid . | Receptor Selectivity KD (nmol/L) . | Transcriptional Activation AC50 (nmol/L) . | MW (g/L) . | ||||
|---|---|---|---|---|---|---|---|
| RARα . | RARβ . | RARγ . | RARα . | RARβ . | RARγ . | ||
| CD367 | 5.3 | 2.5 | 1.3 | 0.23 | 0.37 | 0.25 | 300 |
| CD336 | 8.0 | 131 | 450 | 0.36 | 24.5 | 27.8 | 357 |
| CD2019 | 1100 | 26 | 160 | 19.8 | 3.8 | 46.9 | 375 |
| CD437 | 6500 | 2480 | 77 | 140 | 28.4 | 7.3 | 398 |
| Retinoid . | Receptor Selectivity KD (nmol/L) . | Transcriptional Activation AC50 (nmol/L) . | MW (g/L) . | ||||
|---|---|---|---|---|---|---|---|
| RARα . | RARβ . | RARγ . | RARα . | RARβ . | RARγ . | ||
| CD367 | 5.3 | 2.5 | 1.3 | 0.23 | 0.37 | 0.25 | 300 |
| CD336 | 8.0 | 131 | 450 | 0.36 | 24.5 | 27.8 | 357 |
| CD2019 | 1100 | 26 | 160 | 19.8 | 3.8 | 46.9 | 375 |
| CD437 | 6500 | 2480 | 77 | 140 | 28.4 | 7.3 | 398 |
Abbreviation: MW, molecular weights.
Data from Bernard et al.33