Table 2. Major Peripheral Blood Cell... | American Society of Hematology

Table 2.

Major Peripheral Blood Cell Counts 10 Days After 6 Gy TBI and IV TPO Administration at Different Timepoints After TBI

Time Relative to TBI	TPO Dose (μg)	n	Red Blood Cells (×10¹²/L)	White Blood Cells (×10⁹/L)	Platelets (×10⁹/L)
—	—	14	7.2 ± 0.5^†	0.4 ± 0.1^†	144 ± 62^†
0	0.3	12	8.7 ± 0.5^*	1.0 ± 0.2^*	838 ± 116^*
2	0.3	6	8.8 ± 0.5^*	1.0 ± 0.1^*	765 ± 119^*
4	0.3	6	8.2 ± 0.5^*	0.7 ± 0.1^*^†	658 ± 140^*^†
6	0.3	6	8.3 ± 0.3^*	0.5 ± 0.1^*^†	691 ± 77^*^†
8	0.3	6	7.8 ± 0.3^*^†	0.5 ± 0.1^†	504 ± 88^*^†
24	0.3	3	7.5 ± 0.2^†	0.3 ± 0.1^†	424 ± 143^*^†
Normal mice	—	19	10.2 ± 0.6	5.3 ± 1.9	1,123 ± 89

Time Relative to TBI	TPO Dose (μg)	n	Red Blood Cells (×10¹²/L)	White Blood Cells (×10⁹/L)	Platelets (×10⁹/L)
—	—	14	7.2 ± 0.5^†	0.4 ± 0.1^†	144 ± 62^†
0	0.3	12	8.7 ± 0.5^*	1.0 ± 0.2^*	838 ± 116^*
2	0.3	6	8.8 ± 0.5^*	1.0 ± 0.1^*	765 ± 119^*
4	0.3	6	8.2 ± 0.5^*	0.7 ± 0.1^*^†	658 ± 140^*^†
6	0.3	6	8.3 ± 0.3^*	0.5 ± 0.1^*^†	691 ± 77^*^†
8	0.3	6	7.8 ± 0.3^*^†	0.5 ± 0.1^†	504 ± 88^*^†
24	0.3	3	7.5 ± 0.2^†	0.3 ± 0.1^†	424 ± 143^*^†
Normal mice	—	19	10.2 ± 0.6	5.3 ± 1.9	1,123 ± 89

*Significantly different from control mice.

Significantly different from the 0-hour treatment group.