Gene Frequencies and Amino Acid Variations of Adhesion Molecules in Japanese Subjects
| Adhesion Molecule . | Chr. No.* . | Codon . | Amino Acid Substitution . | Gene Frequency-151 . | |
|---|---|---|---|---|---|
| CD2 (LFA-2) | 1 | 266 | CAC (His) → CAA (Gln) | H: 0.68 | Q: 0.32 |
| CD28 (T44) | 2 | Not detected | |||
| CD31 (PECAM-1) | 17 | 80 | GTG (Val) → ATG (Met) | V: 0.99 | M: 0.01 |
| 125 | GTG (Val) → CTG (Leu) | V: 0.55 | L: 0.45 | ||
| 563 | AGC (Ser) → AAC (Asn) | S: 0.52 | N: 0.48 | ||
| 670 | AGA (Arg) → GGA (Gly) | R: 0.52 | G: 0.48 | ||
| CD34 | 1 | Not detected | |||
| CD36 (GPIV) | 7 | Not detected | |||
| CD42 (GPIb) | 17 | 161 | ACG (Thr) → ATG (Met) | T: 0.89 | M: 0.11 |
| CD44 (Pgp-1) | 11 | Not detected | |||
| CD48 (Blast-1) | 1 | Not detected | |||
| CD49b (VLA-2, GPIa) | 5 | 505 | GAG (Glu) → AAG (Lys) | E: 0.97 | K: 0.03 |
| CD54 (ICAM-1) | 19 | 469 | AAG (Lys) → GAG (Glu) | K: 0.61 | E: 0.39 |
| CD62L (LECAM-1) | 1 | 213 | CCT (Pro) → TCT (Ser) | P: 0.8 | S: 0.2 |
| CD86 (B70) | Not detected | ||||
| CD102 (ICAM-2) | 17 | 256 | CGG (Arg) → CAG (Gln) | R: 0.995 | Q: 0.005 |
| CD106 (VCAM-1) | 1 | Not detected | |||
| Adhesion Molecule . | Chr. No.* . | Codon . | Amino Acid Substitution . | Gene Frequency-151 . | |
|---|---|---|---|---|---|
| CD2 (LFA-2) | 1 | 266 | CAC (His) → CAA (Gln) | H: 0.68 | Q: 0.32 |
| CD28 (T44) | 2 | Not detected | |||
| CD31 (PECAM-1) | 17 | 80 | GTG (Val) → ATG (Met) | V: 0.99 | M: 0.01 |
| 125 | GTG (Val) → CTG (Leu) | V: 0.55 | L: 0.45 | ||
| 563 | AGC (Ser) → AAC (Asn) | S: 0.52 | N: 0.48 | ||
| 670 | AGA (Arg) → GGA (Gly) | R: 0.52 | G: 0.48 | ||
| CD34 | 1 | Not detected | |||
| CD36 (GPIV) | 7 | Not detected | |||
| CD42 (GPIb) | 17 | 161 | ACG (Thr) → ATG (Met) | T: 0.89 | M: 0.11 |
| CD44 (Pgp-1) | 11 | Not detected | |||
| CD48 (Blast-1) | 1 | Not detected | |||
| CD49b (VLA-2, GPIa) | 5 | 505 | GAG (Glu) → AAG (Lys) | E: 0.97 | K: 0.03 |
| CD54 (ICAM-1) | 19 | 469 | AAG (Lys) → GAG (Glu) | K: 0.61 | E: 0.39 |
| CD62L (LECAM-1) | 1 | 213 | CCT (Pro) → TCT (Ser) | P: 0.8 | S: 0.2 |
| CD86 (B70) | Not detected | ||||
| CD102 (ICAM-2) | 17 | 256 | CGG (Arg) → CAG (Gln) | R: 0.995 | Q: 0.005 |
| CD106 (VCAM-1) | 1 | Not detected | |||
*Chromosome number.
Calculated from random Japanese population; number of DNA samples, 209.