Table 6.

Causes of Death in Hairy Cell Leukemia Patients Following Cladribine

Causes of Death (No. of Patients) Months From First Cladribine Therapy
Second malignancies (7) 
 Adenocarcinoma of stomach, metastatic  32  
 Adenocarcinoma of colon  44  
 Melanoma, metastatic  63  
 Hodgkin’s disease  11  
 Neuroendocrine tumor, bladder  50 
 Low-grade non-Hodgkin’s lymphoma  17  
 Adenocarcinoma of prostate, metastatic  14  
Hairy cell leukemia (3) 66, 58, 28  
Cardiac or cerebrovascular events (7) 
 Arrhythmia  7, 73  
 Myocardial infarction 1, 39, 48, 40  
 Stroke  63  
Infectious complications (3)  
 Septicemia (Acinetobacter)  3  
 Adult respiratory distress syndrome  12  
 Septic shock  1  
Unknown (1) 50 
Causes of Death (No. of Patients) Months From First Cladribine Therapy
Second malignancies (7) 
 Adenocarcinoma of stomach, metastatic  32  
 Adenocarcinoma of colon  44  
 Melanoma, metastatic  63  
 Hodgkin’s disease  11  
 Neuroendocrine tumor, bladder  50 
 Low-grade non-Hodgkin’s lymphoma  17  
 Adenocarcinoma of prostate, metastatic  14  
Hairy cell leukemia (3) 66, 58, 28  
Cardiac or cerebrovascular events (7) 
 Arrhythmia  7, 73  
 Myocardial infarction 1, 39, 48, 40  
 Stroke  63  
Infectious complications (3)  
 Septicemia (Acinetobacter)  3  
 Adult respiratory distress syndrome  12  
 Septic shock  1  
Unknown (1) 50 
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