Table 4.

Nonlethal Delayed Adverse Events

Adverse Event (No. of Patients) Months From First Cladribine Therapy
Infections  
 Herpes zoster, dermatomal (7)  10, 18, 20, 24, 41, 42, 69  
 Hepatitis C (2)  31, 51 
 Mycobacterium tuberculosis (1)  21  
 Mycobacterium chelonei (1)  38  
Cardiac or cerebrovascular 
 Myocardial infarction (1)  43  
 Stroke (1)  53 
Pulmonary  
 Pneumonia, etiology undetermined (2)  24, 52  
 Interstitial lung disease (1)  44  
 Pulmonary embolism (1)  66  
Neurological  
 Peripheral neuropathy (2)  9, 25  
 Transverse myelitis (1)  54  
Miscellaneous 
 Thyrotoxicosis (2)  17, 54  
 Psoriatic arthropathy (1) 34  
 Polymyalgia rheumatica (1)  36 
Adverse Event (No. of Patients) Months From First Cladribine Therapy
Infections  
 Herpes zoster, dermatomal (7)  10, 18, 20, 24, 41, 42, 69  
 Hepatitis C (2)  31, 51 
 Mycobacterium tuberculosis (1)  21  
 Mycobacterium chelonei (1)  38  
Cardiac or cerebrovascular 
 Myocardial infarction (1)  43  
 Stroke (1)  53 
Pulmonary  
 Pneumonia, etiology undetermined (2)  24, 52  
 Interstitial lung disease (1)  44  
 Pulmonary embolism (1)  66  
Neurological  
 Peripheral neuropathy (2)  9, 25  
 Transverse myelitis (1)  54  
Miscellaneous 
 Thyrotoxicosis (2)  17, 54  
 Psoriatic arthropathy (1) 34  
 Polymyalgia rheumatica (1)  36 
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