Table 1.

Patient Demographics

No. of patients  358  
Prior therapy  
 None  179 
 Splenectomy alone  44  
 Interferon alone  78 
 Splenectomy, interferon  47  
 Splenectomy, interferon, 2′-deoxycoformycin  4  
 Interferon, 2′-deoxycoformycin  
 2′-Deoxycoformycin alone  1  
 Other regimens  
Spleen size  
 Splenectomized  98  
 No splenomegaly 71  
 Mild (1-2 fingerbreadths)  50  
 Moderate (3-4 fingerbreadths)  58  
 Massive (greater than 4 fingerbreadths) 76  
 Unknown  5  
Lymphadenopathy  109  
Peripheral blood hematologic parameters  
 Absolute neutrophil count (×109/L)  
  Median (range) 0.9 (0.1-12.5)  
 Hemoglobin level (g/dL) 
  Median (range)  11.3 (4.6-16.6)  
 Platelets (×109/L)  
  Median (range) 81 (7-575)  
Peripheral blood immunophenotypic profile  
 Typical for hairy cell leukemia (CD11c, CD25, and CD103 all positive)  174  
 Atypical for hairy cell leukemia (one or more markers negative)  35 
 Not done  149  
Bone marrow infiltration by hairy cells (percentage)  
 Median  80  
 Range 1-100 
No. of patients  358  
Prior therapy  
 None  179 
 Splenectomy alone  44  
 Interferon alone  78 
 Splenectomy, interferon  47  
 Splenectomy, interferon, 2′-deoxycoformycin  4  
 Interferon, 2′-deoxycoformycin  
 2′-Deoxycoformycin alone  1  
 Other regimens  
Spleen size  
 Splenectomized  98  
 No splenomegaly 71  
 Mild (1-2 fingerbreadths)  50  
 Moderate (3-4 fingerbreadths)  58  
 Massive (greater than 4 fingerbreadths) 76  
 Unknown  5  
Lymphadenopathy  109  
Peripheral blood hematologic parameters  
 Absolute neutrophil count (×109/L)  
  Median (range) 0.9 (0.1-12.5)  
 Hemoglobin level (g/dL) 
  Median (range)  11.3 (4.6-16.6)  
 Platelets (×109/L)  
  Median (range) 81 (7-575)  
Peripheral blood immunophenotypic profile  
 Typical for hairy cell leukemia (CD11c, CD25, and CD103 all positive)  174  
 Atypical for hairy cell leukemia (one or more markers negative)  35 
 Not done  149  
Bone marrow infiltration by hairy cells (percentage)  
 Median  80  
 Range 1-100 
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