Proportionate Expression of IgM VH Gene Subgroups
| Controls Mean SD Normal Range . | VH1 . | VH 2 . | VH3 . | VH4 . | VH5 . | VH6 . |
|---|---|---|---|---|---|---|
| 12 5 3-22 . | 1 1 0-4 . | 55 7 40-69 . | 26 5 15-37 . | 4 2 0-8 . | 2 2 0-6 . | |
| Group I | ||||||
| HO | 3 | 4 | 11 | 66 | 9 | 7 |
| HP | 13 | 5 | 20 | 49 | 9 | 3 |
| HQ | 1 | 0 | 11 | 86 | 2 | 0 |
| HR | 21 | 1 | 30 | 48 | 1 | 0 |
| HS | 23 | 1 | 47 | 26 | 3 | 1 |
| HT | 4 | 1 | 80 | 14 | 1 | 1 |
| HU | 4 | 3 | 82 | 11 | 1 | 1 |
| HV | 3 | 1 | 75 | 15 | 4 | 3 |
| HW | 27 | 1 | 36 | 30 | 6 | 1 |
| Group II | ||||||
| HA | 72 | 2 | 7 | 15 | 1 | 2 |
| HB | 48 | 4 | 28 | 16 | 3 | 1 |
| HC | 4 | 8 | 52 | 11 | 14 | 11 |
| HD | 16 | 8 | 43 | 7 | 22 | 4 |
| HE | 4 | 11 | 40 | 29 | 9 | 7 |
| Group III | ||||||
| HF | 34 | 4 | 48 | 11 | 3 | 1 |
| HG | 61 | 1 | 27 | 11 | 1 | 1 |
| HH | 5 | 4 | 64 | 26 | 1 | 1 |
| HI | 21 | 3 | 42 | 30 | 2 | 2 |
| HJ | 18 | 4 | 48 | 26 | 2 | 2 |
| HK | 23 | 6 | 49 | 7 | 9 | 6 |
| HL | 8 | 1 | 68 | 20 | 2 | 1 |
| HM | 9 | 4 | 63 | 15 | 5 | 3 |
| HN | 14 | 3 | 61 | 18 | 4 | 1 |
| Group IV | ||||||
| H1 | 25 | 4 | 58 | 13 | 1 | 0 |
| H3 | 23 | 8 | 27 | 18 | 18 | 6 |
| H5 | 6 | 8 | 11 | 13 | 58 | 4 |
| H6 | 8 | 5 | 5 | 63 | 6 | 12 |
| H7 | 5 | 7 | 62 | 10 | 10 | 5 |
| H8 | 12 | 4 | 48 | 27 | 6 | 2 |
| H10 | 13 | 7 | 46 | 19 | 11 | 4 |
| H17 | 13 | 4 | 54 | 28 | 1 | 0 |
| H18 | 11 | 1 | 51 | 31 | 4 | 3 |
| H19 | 5 | 1 | 73 | 16 | 6 | 0 |
| H20 | 11 | 7 | 39 | 32 | 7 | 4 |
| H21 | 19 | 3 | 57 | 15 | 4 | 2 |
| H22 | 6 | 11 | 59 | 15 | 4 | 6 |
| H23 | 8 | 5 | 42 | 28 | 15 | 2 |
| Controls Mean SD Normal Range . | VH1 . | VH 2 . | VH3 . | VH4 . | VH5 . | VH6 . |
|---|---|---|---|---|---|---|
| 12 5 3-22 . | 1 1 0-4 . | 55 7 40-69 . | 26 5 15-37 . | 4 2 0-8 . | 2 2 0-6 . | |
| Group I | ||||||
| HO | 3 | 4 | 11 | 66 | 9 | 7 |
| HP | 13 | 5 | 20 | 49 | 9 | 3 |
| HQ | 1 | 0 | 11 | 86 | 2 | 0 |
| HR | 21 | 1 | 30 | 48 | 1 | 0 |
| HS | 23 | 1 | 47 | 26 | 3 | 1 |
| HT | 4 | 1 | 80 | 14 | 1 | 1 |
| HU | 4 | 3 | 82 | 11 | 1 | 1 |
| HV | 3 | 1 | 75 | 15 | 4 | 3 |
| HW | 27 | 1 | 36 | 30 | 6 | 1 |
| Group II | ||||||
| HA | 72 | 2 | 7 | 15 | 1 | 2 |
| HB | 48 | 4 | 28 | 16 | 3 | 1 |
| HC | 4 | 8 | 52 | 11 | 14 | 11 |
| HD | 16 | 8 | 43 | 7 | 22 | 4 |
| HE | 4 | 11 | 40 | 29 | 9 | 7 |
| Group III | ||||||
| HF | 34 | 4 | 48 | 11 | 3 | 1 |
| HG | 61 | 1 | 27 | 11 | 1 | 1 |
| HH | 5 | 4 | 64 | 26 | 1 | 1 |
| HI | 21 | 3 | 42 | 30 | 2 | 2 |
| HJ | 18 | 4 | 48 | 26 | 2 | 2 |
| HK | 23 | 6 | 49 | 7 | 9 | 6 |
| HL | 8 | 1 | 68 | 20 | 2 | 1 |
| HM | 9 | 4 | 63 | 15 | 5 | 3 |
| HN | 14 | 3 | 61 | 18 | 4 | 1 |
| Group IV | ||||||
| H1 | 25 | 4 | 58 | 13 | 1 | 0 |
| H3 | 23 | 8 | 27 | 18 | 18 | 6 |
| H5 | 6 | 8 | 11 | 13 | 58 | 4 |
| H6 | 8 | 5 | 5 | 63 | 6 | 12 |
| H7 | 5 | 7 | 62 | 10 | 10 | 5 |
| H8 | 12 | 4 | 48 | 27 | 6 | 2 |
| H10 | 13 | 7 | 46 | 19 | 11 | 4 |
| H17 | 13 | 4 | 54 | 28 | 1 | 0 |
| H18 | 11 | 1 | 51 | 31 | 4 | 3 |
| H19 | 5 | 1 | 73 | 16 | 6 | 0 |
| H20 | 11 | 7 | 39 | 32 | 7 | 4 |
| H21 | 19 | 3 | 57 | 15 | 4 | 2 |
| H22 | 6 | 11 | 59 | 15 | 4 | 6 |
| H23 | 8 | 5 | 42 | 28 | 15 | 2 |
IgM VH gene subgroup levels of blood B cells from HIV-infected persons and seronegative control subjects. At the top of each column is the Ig VH gene subgroup. The top row provides the mean percent levels of each Ig VH gene subgroup for control subjects. The next row indicates the standard deviation (SD) about the mean level for each subgroup of the control group. The next row provides the ranges for the proportions of each Ig VH gene subgroup seen among the control group. The following rows provide the proportions of each Ig VH gene subgroup for each HIV-infected person in Groups I through IV. The individual patient identifier or code is provided in the far left-hand column. Shaded areas represent aberrancy in the expression of Ig VH genes.