Effect of ISIS 2302 on the Modified Russel Viper Venom Time
| Plasma . | RVV-Xa . | Control (sec) . | 50 μg/ml ISIS 2302 . |
|---|---|---|---|
| Normal | 0.2 nmol/L | 32.1 ± 0.8 | 32.2 ± 0.6 |
| FV deficient | 0.2 nmol/L | >200 | ND |
| Plasma . | RVV-Xa . | Control (sec) . | 50 μg/ml ISIS 2302 . |
|---|---|---|---|
| Normal | 0.2 nmol/L | 32.1 ± 0.8 | 32.2 ± 0.6 |
| FV deficient | 0.2 nmol/L | >200 | ND |
The factor X activator purified from Russel viper venom and 2% (vol/vol) rabbit brain cephalin were incubated with normal or factor V–deficient plasma for 30 seconds and recalcified as described. The clotting times are expressed as the mean (sec) ± SD.
Abbreviation: ND, not determined.