Deaths in Chronic Phase
| Treatment Arm . | IFN-α Dose (mIU/m2/d) . | Duration of IFN-α Treatment (mo) . | Time from D/C IFN-α to Death (mo) . | Overall Survival (mo) . | Age at Death (yr) . | Causes of Death . |
|---|---|---|---|---|---|---|
| IFN-α | 4.0 | 2 | 1 | 3 | 45 | Infection, acute, nonidentified |
| IFN-α | 1.5 | 2 | 6 | 8 | 63 | Cardiac, congestive heart failure |
| IFN-α | 1.2 | 1 | 9 | 10 | 69 | Cardiac, congestive heart failure |
| IFN-α | 4.2 | 10 | 0 | 10 | 66 | Gastric bleeding, liver cyrrhosis at necropsy |
| IFN-α | 4.0 | 99 | 0 | 99 | 47 | Cardiac, myocardial infarctus |
| IFN-α | 1.3 | 65 | 3 | 68 | 68 | Vascular, cerebral, thrombotic |
| IFN-α | 4.3 | 89 | 2 | 91 | 71 | Vascular, cerebral, hemorrhagic |
| IFN-α | 4.2 | 73 | 4 | 77 | 71 | Cancer, bronchogenic |
| IFN-α | 4.1 | 72 | 19 | 91 | 73 | Cancer, liver |
| CHT | — | — | — | 14 | 58 | Infection, pneumonitis |
| CHT | — | — | — | 64 | 63 | Vascular, cerebral, undefined |
| CHT | — | — | — | 32 | 65 | Cancer, pharingeal |
| CHT | — | — | — | 38 | 59 | Cancer, pancreatic |
| CHT | — | — | — | 67 | 61 | Cancer, bronchogenic |
| Treatment Arm . | IFN-α Dose (mIU/m2/d) . | Duration of IFN-α Treatment (mo) . | Time from D/C IFN-α to Death (mo) . | Overall Survival (mo) . | Age at Death (yr) . | Causes of Death . |
|---|---|---|---|---|---|---|
| IFN-α | 4.0 | 2 | 1 | 3 | 45 | Infection, acute, nonidentified |
| IFN-α | 1.5 | 2 | 6 | 8 | 63 | Cardiac, congestive heart failure |
| IFN-α | 1.2 | 1 | 9 | 10 | 69 | Cardiac, congestive heart failure |
| IFN-α | 4.2 | 10 | 0 | 10 | 66 | Gastric bleeding, liver cyrrhosis at necropsy |
| IFN-α | 4.0 | 99 | 0 | 99 | 47 | Cardiac, myocardial infarctus |
| IFN-α | 1.3 | 65 | 3 | 68 | 68 | Vascular, cerebral, thrombotic |
| IFN-α | 4.3 | 89 | 2 | 91 | 71 | Vascular, cerebral, hemorrhagic |
| IFN-α | 4.2 | 73 | 4 | 77 | 71 | Cancer, bronchogenic |
| IFN-α | 4.1 | 72 | 19 | 91 | 73 | Cancer, liver |
| CHT | — | — | — | 14 | 58 | Infection, pneumonitis |
| CHT | — | — | — | 64 | 63 | Vascular, cerebral, undefined |
| CHT | — | — | — | 32 | 65 | Cancer, pharingeal |
| CHT | — | — | — | 38 | 59 | Cancer, pancreatic |
| CHT | — | — | — | 67 | 61 | Cancer, bronchogenic |
Fourteen patients died in chronic phase, nine in the IFN-α arm and five in the chemotherapy arm.
Abbreviations: CHT, chemotherapy; D/C, discontinuation of.