Table 2. IFN- Arm. Distribution by the... | American Society of Hematology

Table 2.

IFN- Arm. Distribution by the Years of Treatment of the Side Effects That Caused Treatment Discontinuation

Side Effects	Years of Treatment
Side Effects	1	2-3	4-5	6 or More	Total
Fatigue, fever, pain, headache	10	6	5	4	25 (37%)
Anorexia, nausea, diarrhea	8	6	0	0	14 (21%)
Neurologic, “central” ^*	1	2	3	0	6 (9%)
Neurologic, “peripheral” ^†	2	2	1	0	5 (7%)
Hematologic	2	2	2	0	6 (9%)
Skin, itching, alopecia	3	2	2	0	7 (10%)
Liver	0	1	1	0	2 (3%)
Allergic reaction	2	0	0	0	2 (3%)
Total	28	21	14	4	67 (100%)

Side Effects	Years of Treatment
Side Effects	1	2-3	4-5	6 or More	Total
Fatigue, fever, pain, headache	10	6	5	4	25 (37%)
Anorexia, nausea, diarrhea	8	6	0	0	14 (21%)
Neurologic, “central” ^*	1	2	3	0	6 (9%)
Neurologic, “peripheral” ^†	2	2	1	0	5 (7%)
Hematologic	2	2	2	0	6 (9%)
Skin, itching, alopecia	3	2	2	0	7 (10%)
Liver	0	1	1	0	2 (3%)
Allergic reaction	2	0	0	0	2 (3%)
Total	28	21	14	4	67 (100%)

Treatment was discontinued in 39 patients overall, but usually more than one side effect contributed to the decision of discontinuing the treatment.

Depression, amnesy, lethargia, psychosis, reversible coma in one case.

Polyneuropathy, mainly sensorial.