Sensitivies of Detection Assays Used to Identify Residual Tumor
| Detection Method . | Sample Source . | Sensitivity . |
|---|---|---|
| Histology | Bone marrow biopsy | 1 in 20 cells |
| ELISA | Serum | 0.1 μg/mL |
| FACS | PBL and BM | 1 in 104 cells |
| Genomic PCR (bcl-2) | PBL and BM | 1 in 105 cells |
| RT-PCR (CDR3) | PBL and BM | 1 in 107 cells |
| Detection Method . | Sample Source . | Sensitivity . |
|---|---|---|
| Histology | Bone marrow biopsy | 1 in 20 cells |
| ELISA | Serum | 0.1 μg/mL |
| FACS | PBL and BM | 1 in 104 cells |
| Genomic PCR (bcl-2) | PBL and BM | 1 in 105 cells |
| RT-PCR (CDR3) | PBL and BM | 1 in 107 cells |
Abbreviations: PBL, peripheral blood lymphocytes; BM, bone marrow.