Table 1.

Results of Therapeutic Trials Using Anti-Idiotype Antibodies

Therapy Patients Treated PR CR CR Durations (years)
Anti-Id  18  8  4  1.5, 4+, 7,-150 9.5+ 
Anti-Id + IFN  12  7  2  9.5+, 10+  
Anti-Id + Chl  13  8  1  2.5  
Anti-Id + IL-2 9  2  1  4.5  
Totals  52  25   
Therapy Patients Treated PR CR CR Durations (years)
Anti-Id  18  8  4  1.5, 4+, 7,-150 9.5+ 
Anti-Id + IFN  12  7  2  9.5+, 10+  
Anti-Id + Chl  13  8  1  2.5  
Anti-Id + IL-2 9  2  1  4.5  
Totals  52  25   

Antibodies were given either alone or in combination with other agents: IFN, alpha interferon; Chl, chlorambucil; IL-2, interleukin-2.

Abbreviations: PR, partial remission; CR, complete remission.

F0-150

Patient 1 received local XRT after a local relapse at 7 years and subsequently has been in continuous and ongoing remission for an additional 9 years.

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