Prospective Comparison of the Platelet Increment, Platelet Recovery and Transfusion Interval After Medium, High, and Very High Doses of Platelets in 13 Children
| . | Medium Dose 2 to 4 × 1011 . | High Dose 4 to 6 × 1011 . | (p) . | Very High Dose >6 × 1011 . | (P) . |
|---|---|---|---|---|---|
| Platelet transfused (1011) | 3.3 ± 0.3 | 4.9 ± 0.6 | 7 ± 0.7 | ||
| Platelet increment (109/L) | 37 ± 28 | 64 ± 33 | (p < .05) | 98 ± 34 | (P < .01) |
| Recovery (%) | 28 ± 19 | 29 ± 17 | NS | 32 ± 15 | NS |
| Time to the next transfusion (days) | 2.5 ± 1 | 3.4 ± 1.5 | (p < .05) | 4.4 ± 1.5 | (P < .05) |
| . | Medium Dose 2 to 4 × 1011 . | High Dose 4 to 6 × 1011 . | (p) . | Very High Dose >6 × 1011 . | (P) . |
|---|---|---|---|---|---|
| Platelet transfused (1011) | 3.3 ± 0.3 | 4.9 ± 0.6 | 7 ± 0.7 | ||
| Platelet increment (109/L) | 37 ± 28 | 64 ± 33 | (p < .05) | 98 ± 34 | (P < .01) |
| Recovery (%) | 28 ± 19 | 29 ± 17 | NS | 32 ± 15 | NS |
| Time to the next transfusion (days) | 2.5 ± 1 | 3.4 ± 1.5 | (p < .05) | 4.4 ± 1.5 | (P < .05) |
Results are expressed as means ± SD.
Abbreviations: NS, not significant; p, statistical difference between medium and high dose; P, statistical difference between high and very high dose. Comparisons were made using a pairedt-test.