Prospective Comparison of the Platelet Increment, Platelet Recovery, and Transfusion Interval After Medium, High, and Very High Doses of Platelets in 69 Adults
| . | Medium Dose 4 to 6 × 1011 . | High Dose 6 to 8 × 1011 . | (p) . | Very High Dose >8 × 1011 . | (P) . |
|---|---|---|---|---|---|
| Platelet transfused (1011) | 4.6 ± 0.6 | 6.5 ± 0.5 | 8.9 ± 0.7 | ||
| Platelet increment (109/L) | 33 ± 22 | 51 ± 29 | (p < .01) | 62 ± 34 | (P < .01) |
| Recovery (%) | 28 ± 13 | 30 ± 15 | NS | 29 ± 13 | NS |
| Time to the next transfusion (days) | 2.6 ± 0.7 | 3.3 ± 1.2 | (p < .01) | 4.1 ± 1.4 | (P < .01) |
| . | Medium Dose 4 to 6 × 1011 . | High Dose 6 to 8 × 1011 . | (p) . | Very High Dose >8 × 1011 . | (P) . |
|---|---|---|---|---|---|
| Platelet transfused (1011) | 4.6 ± 0.6 | 6.5 ± 0.5 | 8.9 ± 0.7 | ||
| Platelet increment (109/L) | 33 ± 22 | 51 ± 29 | (p < .01) | 62 ± 34 | (P < .01) |
| Recovery (%) | 28 ± 13 | 30 ± 15 | NS | 29 ± 13 | NS |
| Time to the next transfusion (days) | 2.6 ± 0.7 | 3.3 ± 1.2 | (p < .01) | 4.1 ± 1.4 | (P < .01) |
Results are expressed as means ± SD.
Abbreviations: NS, not significant; p, statistical difference between medium and high dose; P, statistical difference between high and very high dose. Comparisons were made using a pairedt-test.