Table 2.

Mathematical Analysis of the Kinetics of Engraftment

Disease Phase AUC*Increment†
CP  7.6  0.9 
AP  27.4  0.5  
BP  308  7.2 
Disease Phase AUC*Increment†
CP  7.6  0.9 
AP  27.4  0.5  
BP  308  7.2 

*AUC, Area under the curve (see Materials and Methods).

†

Increment is the percentage of increase in human cell numbers detected in mouse BM per week.

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