Table 2. Clonal Evolution Between... | American Society of Hematology

Table 2.

Clonal Evolution Between Presentation and Relapse in cALL Patients

Patient No.	Time of Relapse^* (mo)	Site of Relapse^†	No. of IgH PCR Products		IgH Fragment Size (bp)
Patient No.	Time of Relapse^* (mo)	Site of Relapse^†	Presentation	Relapse	Presentation	Relapse
47	33	BM, CNS	Multiple	2		80
						90
48	54	BM	4	2	75	100
					100	110
					120
					130
50	28	BM	3^‡	1	75	65
					85
					105
64	11	CNS	3	3	60	80
					70	100
					110	110
65	61	BM	1^1-153	2	110	110
						125
44	39	BM	1^1-155	2	100	100
						115

Patient No.	Time of Relapse^* (mo)	Site of Relapse^†	No. of IgH PCR Products		IgH Fragment Size (bp)
Patient No.	Time of Relapse^* (mo)	Site of Relapse^†	Presentation	Relapse	Presentation	Relapse
47	33	BM, CNS	Multiple	2		80
						90
48	54	BM	4	2	75	100
					100	110
					120
					130
50	28	BM	3^‡	1	75	65
					85
					105
64	11	CNS	3	3	60	80
					70	100
					110	110
65	61	BM	1^1-153	2	110	110
						125
44	39	BM	1^1-155	2	100	100
						115

*Time interval between presentation and relapse.

BM, bone marrow; CNS, central nervous system.

Oligoclonal at presentation and at end of treatment.

Oligoclonal at presentation by Southern blotting.

Oligoclonal at end of treatment.