Table 2. Virological and Immunological... | American Society of Hematology

Table 2.

Virological and Immunological Features of the 135 Hemophilic Patients With Chronic Hepatitis C According to the Presence or Absence of Serum Cryoglobulins

Serum Markers	All Patients (n = 135)	Cryoglobulins (+) (n = 42)	Cryoglobulins (−) (n = 93)	PValue^*
Anti-HCV	135 (100%)	42 (100%)	93 (100%)	NS
HCV-RNA	114 (84%)	40 (95%)	74 (80%)	<.05
HBsAg	9 (7%)	7 (17%)	2 (2%)	NS
HBV-DNA	14 (10%)	2 (5%)	12 (13%)	NS
Anti-HIV	67 (50%)	24 (57%)	43 (46%)	NS
Antitissue antibodies (titer ≥1:40)	31/123 (25%)	8/38 (21%)	23/85 (27%)	NS
Rheumatoid factor >60 UI/mL	13/129 (10%)	8/40 (20%)	5/89 (6%)	<.05
IgG (mg/dL)^†	2,066 ± 630	2,354 ± 682	1,928 ± 557	<.0005
IgM (mg/dL)^†	269 ± 240	323 ± 226	244 ± 243	<.05
C₄ (mg/dL)^†	22 ± 8	19 ± 8	24 ± 8	<.05

Serum Markers	All Patients (n = 135)	Cryoglobulins (+) (n = 42)	Cryoglobulins (−) (n = 93)	PValue^*
Anti-HCV	135 (100%)	42 (100%)	93 (100%)	NS
HCV-RNA	114 (84%)	40 (95%)	74 (80%)	<.05
HBsAg	9 (7%)	7 (17%)	2 (2%)	NS
HBV-DNA	14 (10%)	2 (5%)	12 (13%)	NS
Anti-HIV	67 (50%)	24 (57%)	43 (46%)	NS
Antitissue antibodies (titer ≥1:40)	31/123 (25%)	8/38 (21%)	23/85 (27%)	NS
Rheumatoid factor >60 UI/mL	13/129 (10%)	8/40 (20%)	5/89 (6%)	<.05
IgG (mg/dL)^†	2,066 ± 630	2,354 ± 682	1,928 ± 557	<.0005
IgM (mg/dL)^†	269 ± 240	323 ± 226	244 ± 243	<.05
C₄ (mg/dL)^†	22 ± 8	19 ± 8	24 ± 8	<.05

Abbreviation: NS, not significant.

Cryoglobulins (+) v Cryoglobulins (−).

†

Data are mean ± standard deviation.

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