Table 1.

Epidemiological and Clinical Features of the 135 Hemophilic Patients With Chronic Hepatitis C According to the Presence or Absence of Serum Cryoglobulins

Features All Patients n = 135 Cryo- globulins (+) n = 42 Cryo- globulins (−) n = 93P Value
Age, median (range)  31 (10-69) 32 (14-69)  31 (10-66)  NS  
Hemophilia  
 Severe 112 (83%)  38 (90%)  74 (80%)  NS 
 Mild/moderate  23 (17%)  4 (10%)  19 (20%)  NS 
Serum ALT  
 Persistently normal  14 (10%)  2 (4%) 12 (13%)  NS  
 Intermittently high  69 (51%) 20 (48%)  49 (53%)  NS  
 Persistently high 52 (39%)  20 (48%)  32 (34%)  NS  
Cirrhosis 3 (2%)  0   3 (2%)  NS 
Features All Patients n = 135 Cryo- globulins (+) n = 42 Cryo- globulins (−) n = 93P Value
Age, median (range)  31 (10-69) 32 (14-69)  31 (10-66)  NS  
Hemophilia  
 Severe 112 (83%)  38 (90%)  74 (80%)  NS 
 Mild/moderate  23 (17%)  4 (10%)  19 (20%)  NS 
Serum ALT  
 Persistently normal  14 (10%)  2 (4%) 12 (13%)  NS  
 Intermittently high  69 (51%) 20 (48%)  49 (53%)  NS  
 Persistently high 52 (39%)  20 (48%)  32 (34%)  NS  
Cirrhosis 3 (2%)  0   3 (2%)  NS 

Abbreviations: NS, not significant; ALT, alanine aminotransferase.

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