Table 1. Characterization of Inhibitor... | American Society of Hematology

Table 1.

Characterization of Inhibitor IgG

Name	Inhibitor Neutralization by fVIII Domains (%)			Immunoprecipitation of fVIII Domains (IP units/mL)
Name	A2	C2	LCh	A1	A2	B	LCh	C2	C2^-150
MU	≤5	15	94	0	12	0	480,000	187,700	19.7
RI	≤5	26	70	0	781	0	7,755	4,937	5.4
MS	27	30	78	0	204	0.2	18,890	1,667	5.1

Name	Inhibitor Neutralization by fVIII Domains (%)			Immunoprecipitation of fVIII Domains (IP units/mL)
Name	A2	C2	LCh	A1	A2	B	LCh	C2	C2^-150
MU	≤5	15	94	0	12	0	480,000	187,700	19.7
RI	≤5	26	70	0	781	0	7,755	4,937	5.4
MS	27	30	78	0	204	0.2	18,890	1,667	5.1

The inhibitor neutralization results were previously reported15 and are expressed as percent of a control without inhibitor. The calculation of IP units/mL is described in Materials and Methods.

F0-150

IP titers of IgGs after removal of anti-C2 antibodies.

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