Incidence of Platelet Transfusions in the 4 Groups According to the Risk Model
| Calculated Incidence (%; 95% CI) | Observed Incidence | ||||||||||
| Validation Series | |||||||||||
| CLB 1996 | CLB 1997 | ELYPSE 1 | CLB-NHL | Total | |||||||
| No. | % (95% CI) | No. | % (95% CI) | No. | % (95% CI) | No. | % (95% CI) | No. | % (95% CI) | ||
| ≥3 risk factors | 44.5 (37-52) | 9/20 | 45 (23-67) | 4/12 | 33.3 (6-60) | 0/2 | 0 | 4/8 | 50 (15-85) | 17/423-150 | 40 (25-55) |
| 2 risk factors | 13 (10-17) | 14/109 | 12.8 (7-19) | 4/41 | 9.8 (1-19) | 3/18 | 17 (0-34) | 5/29 | 17 (3-31) | 26/197 | 13 (8-18) |
| 1 risk factor | 7 (5-10) | 24/330 | 7.3 (5-10) | 3/122 | 2.5 (0-5) | 5/73 | 7 (1-13) | 2/75 | 3 (0-7) | 34/600 | 5.3 (3.5-7) |
| No risk factor | 1.5 (1-2) | 9/592 | 1.5 (0.5-2.5) | 2/137 | 1.5 (0-3.5) | 2/202 | 1 (0-2) | 0/37 | 0 | 13/968 | 1.3 (0.5-2) |
| Calculated Incidence (%; 95% CI) | Observed Incidence | ||||||||||
| Validation Series | |||||||||||
| CLB 1996 | CLB 1997 | ELYPSE 1 | CLB-NHL | Total | |||||||
| No. | % (95% CI) | No. | % (95% CI) | No. | % (95% CI) | No. | % (95% CI) | No. | % (95% CI) | ||
| ≥3 risk factors | 44.5 (37-52) | 9/20 | 45 (23-67) | 4/12 | 33.3 (6-60) | 0/2 | 0 | 4/8 | 50 (15-85) | 17/423-150 | 40 (25-55) |
| 2 risk factors | 13 (10-17) | 14/109 | 12.8 (7-19) | 4/41 | 9.8 (1-19) | 3/18 | 17 (0-34) | 5/29 | 17 (3-31) | 26/197 | 13 (8-18) |
| 1 risk factor | 7 (5-10) | 24/330 | 7.3 (5-10) | 3/122 | 2.5 (0-5) | 5/73 | 7 (1-13) | 2/75 | 3 (0-7) | 34/600 | 5.3 (3.5-7) |
| No risk factor | 1.5 (1-2) | 9/592 | 1.5 (0.5-2.5) | 2/137 | 1.5 (0-3.5) | 2/202 | 1 (0-2) | 0/37 | 0 | 13/968 | 1.3 (0.5-2) |
The observed incidences of differences in platelet transfusions in risk groups ≥3, 2, 1, or 0 risk factors were not statistically different among the 4 series (χ2 = 2.09,P = .55 for comparison of patients with 3 or all risk factors; χ2 = 1.04, P = .79 for comparison of patients with 2 risk factors; χ2 = 5.77,P = .12 for comparison of patients with 1 risk factor; and χ2 = 0.85, P = .83 for comparison of patients with no risk factors).
Including 3 patients with 4 risk factors.