Effects of GVHD on the PB Cells, BM Cellularity, and CFU-GM
| . | PB Cell Counts . | Total No. of BM Cells (×106) . | CFU-GM/105 . | ||
|---|---|---|---|---|---|
| Total Leukocyte (/μL) . | Hematocrit (%) . | Platelet (×104/μL) . | |||
| BDF1 | 3,150 ± 45 | 54.1 ± 3.0 | 69.2 ± 7.4 | 34.1 ± 1.7 | 53.8 ± 10.3 |
| B6/BDF1 | 2,160 ± 307-150 | 37.6 ± 0.4-150 | 23.4 ± 8.7-150 | 6.2 ± 1.8-150 | 29.7 ± 7.2-150 |
| D2/BDF1 | 3,433 ± 553 | 51.0 ± 6.2 | 62.3 ± 5.7 | 36.0 ± 7.4 | 54.6 ± 6.4 |
| . | PB Cell Counts . | Total No. of BM Cells (×106) . | CFU-GM/105 . | ||
|---|---|---|---|---|---|
| Total Leukocyte (/μL) . | Hematocrit (%) . | Platelet (×104/μL) . | |||
| BDF1 | 3,150 ± 45 | 54.1 ± 3.0 | 69.2 ± 7.4 | 34.1 ± 1.7 | 53.8 ± 10.3 |
| B6/BDF1 | 2,160 ± 307-150 | 37.6 ± 0.4-150 | 23.4 ± 8.7-150 | 6.2 ± 1.8-150 | 29.7 ± 7.2-150 |
| D2/BDF1 | 3,433 ± 553 | 51.0 ± 6.2 | 62.3 ± 5.7 | 36.0 ± 7.4 | 54.6 ± 6.4 |
The BDF1 mice were injected with either 5 × 107 of B6 spleen cells (B6/BDF1) or 9 × 107 of D2 cells (D2/BDF1). The PB cell counts, BM cellularity, and CFU-GM were examined on day 14 after transfer. The results from three to five mice were expressed as the mean ± SEM.
Significant decrease versus the uninjected control BDF1 mice (P < .01).