Frequency of HSCs in Post–5-FU Regenerating p53+/+ and p53−/− BMCs
| Immunophenotype . | Frequency of HSCs (%) . | ||
|---|---|---|---|
| Source of Cells: . | p53+/+ . | p53−/− . | |
| Lin− Sca-1+ c-Kit+ CD34low/− | 0.022 ± 0.020 | 0.021 ± 0.016 | |
| Lin− Sca-1+c-Kit+ CD34high/+ | 0.037 ± 0.021 | 0.137 ± 0.021 | |
| Lin−Sca-1+ c-Kit+ | 0.059 | 0.158 | |
| Immunophenotype . | Frequency of HSCs (%) . | ||
|---|---|---|---|
| Source of Cells: . | p53+/+ . | p53−/− . | |
| Lin− Sca-1+ c-Kit+ CD34low/− | 0.022 ± 0.020 | 0.021 ± 0.016 | |
| Lin− Sca-1+c-Kit+ CD34high/+ | 0.037 ± 0.021 | 0.137 ± 0.021 | |
| Lin−Sca-1+ c-Kit+ | 0.059 | 0.158 | |
Cell subpopulations were obtained after immunosorting p53−/− or p53+/+ BMCs collected on day 6 after 5-FU treatment. Results are mean ± standard deviation from three independent experiments.