Table 1. Clinical and Biologic... | American Society of Hematology

Table 1.

Clinical and Biologic Characteristics of Patients With Indolent SMCD

Patient ID	Age/Sex	Tissues With MC Infiltration	PB	BM Dysplasia	% BMMC	Tryptase^-150	Mediator-Related Symptoms	Therapy^-151
1	26/M	S, BM	N	Dyserithro	0.20	ND	No	None
2	67/M	S, BM, B	N	No	0.42	4.2	Pruritus	Anti-H1
								Anti-H2
3	30/M	S, BM	Eos	No	0.43	ND	No	None
4	37/F	S, BM	Eos	No	0.24	ND	No	None
5	67/M	S, BM	Eos	No	0.36	ND	Pruritus	None
6	51/F	S, BM	N	No	0.015	ND	No	None
7	51/F	S, BM, GI, spleen^-152	Eos, anemia^-153	No	0.02	7	Pruritus, flush Syncope, abdominal pain	Anti-H1 Anti-H2 CS
					0.09	ND	No	Anti-H1
								Anti-H2
								CS
8	49/M	S, BM, B, GI, hepatomegaly	Eos	No	0.49	27	Pruritus, flush Syncope, abdominal pain	Anti-H1 Anti-H2 CS Aspirin
					0.29	6	Pruritus, flush abdominal pain	Anti-H1 Anti-H2 CS Aspirin
9	42/F	S, BM, B	Eos	No	0.12	10	Pruritus, flush	Anti-H1
								Anti-H2
								CS
10	33/M	S, BM, GI	N	No	0.15	ND	Pruritus	Anti-H1
								Anti-H2

Patient ID	Age/Sex	Tissues With MC Infiltration	PB	BM Dysplasia	% BMMC	Tryptase^-150	Mediator-Related Symptoms	Therapy^-151
1	26/M	S, BM	N	Dyserithro	0.20	ND	No	None
2	67/M	S, BM, B	N	No	0.42	4.2	Pruritus	Anti-H1
								Anti-H2
3	30/M	S, BM	Eos	No	0.43	ND	No	None
4	37/F	S, BM	Eos	No	0.24	ND	No	None
5	67/M	S, BM	Eos	No	0.36	ND	Pruritus	None
6	51/F	S, BM	N	No	0.015	ND	No	None
7	51/F	S, BM, GI, spleen^-152	Eos, anemia^-153	No	0.02	7	Pruritus, flush Syncope, abdominal pain	Anti-H1 Anti-H2 CS
					0.09	ND	No	Anti-H1
								Anti-H2
								CS
8	49/M	S, BM, B, GI, hepatomegaly	Eos	No	0.49	27	Pruritus, flush Syncope, abdominal pain	Anti-H1 Anti-H2 CS Aspirin
					0.29	6	Pruritus, flush abdominal pain	Anti-H1 Anti-H2 CS Aspirin
9	42/F	S, BM, B	Eos	No	0.12	10	Pruritus, flush	Anti-H1
								Anti-H2
								CS
10	33/M	S, BM, GI	N	No	0.15	ND	Pruritus	Anti-H1
								Anti-H2

Abbreviations: B, bone; BM, bone marrow; BMMC, bone marrow mast cells; GI, gastrointestinal tract; PB, peripheral blood; Eos, eosinophilia; ND, not detected; CS, Cromolyn sodium; N, normal; S, skin.

F0-150

Serum tryptase levels in UI/L.

F0-151

Therapy received at the moment entering the study.

F0-152

Splenomegaly detected by ultrasonography.

F0-153

Iron deficiency anemia.

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