Table 2.

Bone Histomorphometric Analysis of SCID Mice Engrafted With ATL Cells

Parameter Control (n = 6)*SCID-ATL (n = 5)*Unit
BV/TV  14.994 ± 2.191 11.387 ± 0.921 
OV/BV  4.382 ± 0.892 1.719 ± 0.975 
OS/BS  15.376 ± 3.286 6.864 ± 3.423 
ES/BS  8.539 ± 1.161  9.211 ± 1.216  %  
BFR/BV 111.912 ± 20.923 68.58 ± 22.044 mm3/cm3/yr 
Parameter Control (n = 6)*SCID-ATL (n = 5)*Unit
BV/TV  14.994 ± 2.191 11.387 ± 0.921 
OV/BV  4.382 ± 0.892 1.719 ± 0.975 
OS/BS  15.376 ± 3.286 6.864 ± 3.423 
ES/BS  8.539 ± 1.161  9.211 ± 1.216  %  
BFR/BV 111.912 ± 20.923 68.58 ± 22.044 mm3/cm3/yr 

Bone volume was decreased in SCID mice engrafted with ATL cells. OV/BV, OS/BS, and BFR/BV, indices of bone formation, were decreased in ATL mice. In contrast, ES/BS, an indicator of bone resorption, was not. All values were reported as the mean ± standard deviation.

*

Number of mice.

P < .01.

Close Modal

or Create an Account

Close Modal
Close Modal