Table 5. Effect of High-Mg Diet in β... | American Society of Hematology

Table 5.

Effect of High-Mg Diet in β Thal Mice

Parameter	Baseline (n = 6)	Day 14 (n = 6)	Day 28 (n = 6)
Hct (%)	30.9 ± 1.5	34.7 ± 1.0^5-150	35.6 ± 0.6^5-150
Hb (g/dL)	9.5 ± 0.6	10.7 ± 0.5^5-150	11.0 ± 0.4^5-150
MCHC (g/dL)	32.5 ± 1.4	31.2 ± 1.6	30.2 ± 0.4^†
D₅₀	1.103 ± 0.002	1.097 ± 0.001^5-150	1.096 ± 0.001^5-150
Reticulocytes (%)	29.2 ± 1.8	25.2 ± 3.7^5-150	22.0 ± 3.7^5-150
Corrected reticulocyte count (%)	20.0 ± 1.2	19.3 ± 2.8	17.3 ± 2.9
Serum Mg (mmol/L)	1.8 ± 0.2	3.8 ± 0.4^5-150	4.2 ± 0.6^5-150
Erythrocyte Mg (mmol/kg Hb)	8.9 ± 0.2	13.8 ± 0.2^5-150	15.0 ± 0.1^5-150
Cell Na (mmol/kg Hb)	50.3 ± 4.8	49.5 ± 3.9	50.2 ± 5.1
Cell K (mmol/kg Hb)	279 ± 11.5	401 ± 48^5-150	382 ± 21^5-150
Cell Na + K (mmol/kg Hb)	329.3 ± 18	450.8 ± 33^5-150	432.2 ± 12.1^5-150
K-Cl cotransport (mmol/L cells⋅h)	11.3 ± 1.5	6.8 ± 0.8^5-150	5.0 ± 2.3^5-150

Parameter	Baseline (n = 6)	Day 14 (n = 6)	Day 28 (n = 6)
Hct (%)	30.9 ± 1.5	34.7 ± 1.0^5-150	35.6 ± 0.6^5-150
Hb (g/dL)	9.5 ± 0.6	10.7 ± 0.5^5-150	11.0 ± 0.4^5-150
MCHC (g/dL)	32.5 ± 1.4	31.2 ± 1.6	30.2 ± 0.4^†
D₅₀	1.103 ± 0.002	1.097 ± 0.001^5-150	1.096 ± 0.001^5-150
Reticulocytes (%)	29.2 ± 1.8	25.2 ± 3.7^5-150	22.0 ± 3.7^5-150
Corrected reticulocyte count (%)	20.0 ± 1.2	19.3 ± 2.8	17.3 ± 2.9
Serum Mg (mmol/L)	1.8 ± 0.2	3.8 ± 0.4^5-150	4.2 ± 0.6^5-150
Erythrocyte Mg (mmol/kg Hb)	8.9 ± 0.2	13.8 ± 0.2^5-150	15.0 ± 0.1^5-150
Cell Na (mmol/kg Hb)	50.3 ± 4.8	49.5 ± 3.9	50.2 ± 5.1
Cell K (mmol/kg Hb)	279 ± 11.5	401 ± 48^5-150	382 ± 21^5-150
Cell Na + K (mmol/kg Hb)	329.3 ± 18	450.8 ± 33^5-150	432.2 ± 12.1^5-150
K-Cl cotransport (mmol/L cells⋅h)	11.3 ± 1.5	6.8 ± 0.8^5-150	5.0 ± 2.3^5-150

Data are presented as the mean ± SD. Corrected reticulocyte count based on baseline 45.2% Hct of C57BL/6 controls (see Table 1).

P < .005, † P < .05: v baseline.