Table 2.

Effect of Low-Mg Diet in C57BL6 Control Mice

ParameterBaseline (n = 6)Day 14 (n = 6)Day 28 (n = 6)
Hct (%) 43.7 ± 0.8 43.4 ± 1.0  40 ± 2.2* 
Hb (g/dL) 14.2 ± 0.6 13.6 ± 0.4 11.2 ± 1.2* 
MCHC (g/dL) 30.4 ± 1.2 31.5 ± 0.8 32.0 ± 0.4 
D50 1.090 ± 0.001 1.094 ± 0.001* 1.094 ± 0.002* 
Reticulocytes (%) 3.6 ± 0.4 6.1 ± 1.2* 3.1 ± 0.4 
Corrected reticulocyte count (%) 3.6 ± 0.4 6.1 ± 1.2* 2.84 ± 0.4 
Serum Mg (mmol/L) 2.7 ± 0.2 1.3 ± 0.1* 1.4 ± 0.4* 
Erythrocyte Mg (mmol/kg Hb) 9.2 ± 0.4 7.2 ± 0.1* 7.9 ± 0.1* 
Cell Na (mmol/kg Hb) 52.2 ± 2.1  55 ± 2.8 56.5 ± 2.4 
Cell K (mmol/kg Hb)  430 ± 17  324 ± 12*  375 ± 22.3* 
Cell Na + K (mmol/kg Hb)  483 ± 17.2 (6)  379 ± 12 (6)*  431 ± 20 (6)* 
K-Cl cotransport (mmol/L cells⋅h) 4.2 ± 0.5 5.7 ± 0.8* 5.6 ± 1.3* 
ParameterBaseline (n = 6)Day 14 (n = 6)Day 28 (n = 6)
Hct (%) 43.7 ± 0.8 43.4 ± 1.0  40 ± 2.2* 
Hb (g/dL) 14.2 ± 0.6 13.6 ± 0.4 11.2 ± 1.2* 
MCHC (g/dL) 30.4 ± 1.2 31.5 ± 0.8 32.0 ± 0.4 
D50 1.090 ± 0.001 1.094 ± 0.001* 1.094 ± 0.002* 
Reticulocytes (%) 3.6 ± 0.4 6.1 ± 1.2* 3.1 ± 0.4 
Corrected reticulocyte count (%) 3.6 ± 0.4 6.1 ± 1.2* 2.84 ± 0.4 
Serum Mg (mmol/L) 2.7 ± 0.2 1.3 ± 0.1* 1.4 ± 0.4* 
Erythrocyte Mg (mmol/kg Hb) 9.2 ± 0.4 7.2 ± 0.1* 7.9 ± 0.1* 
Cell Na (mmol/kg Hb) 52.2 ± 2.1  55 ± 2.8 56.5 ± 2.4 
Cell K (mmol/kg Hb)  430 ± 17  324 ± 12*  375 ± 22.3* 
Cell Na + K (mmol/kg Hb)  483 ± 17.2 (6)  379 ± 12 (6)*  431 ± 20 (6)* 
K-Cl cotransport (mmol/L cells⋅h) 4.2 ± 0.5 5.7 ± 0.8* 5.6 ± 1.3* 

Data are presented as the mean ± SD.

*

P < .005, † P < .05: v baseline.

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