Effect of Low-Mg Diet in C57BL6 Control Mice
Parameter . | Baseline (n = 6) . | Day 14 (n = 6) . | Day 28 (n = 6) . |
---|---|---|---|
Hct (%) | 43.7 ± 0.8 | 43.4 ± 1.0 | 40 ± 2.2* |
Hb (g/dL) | 14.2 ± 0.6 | 13.6 ± 0.4 | 11.2 ± 1.2* |
MCHC (g/dL) | 30.4 ± 1.2 | 31.5 ± 0.8 | 32.0 ± 0.4† |
D50 | 1.090 ± 0.001 | 1.094 ± 0.001* | 1.094 ± 0.002* |
Reticulocytes (%) | 3.6 ± 0.4 | 6.1 ± 1.2* | 3.1 ± 0.4 |
Corrected reticulocyte count (%) | 3.6 ± 0.4 | 6.1 ± 1.2* | 2.84 ± 0.4 |
Serum Mg (mmol/L) | 2.7 ± 0.2 | 1.3 ± 0.1* | 1.4 ± 0.4* |
Erythrocyte Mg (mmol/kg Hb) | 9.2 ± 0.4 | 7.2 ± 0.1* | 7.9 ± 0.1* |
Cell Na (mmol/kg Hb) | 52.2 ± 2.1 | 55 ± 2.8 | 56.5 ± 2.4† |
Cell K (mmol/kg Hb) | 430 ± 17 | 324 ± 12* | 375 ± 22.3* |
Cell Na + K (mmol/kg Hb) | 483 ± 17.2 (6) | 379 ± 12 (6)* | 431 ± 20 (6)* |
K-Cl cotransport (mmol/L cells⋅h) | 4.2 ± 0.5 | 5.7 ± 0.8* | 5.6 ± 1.3* |
Parameter . | Baseline (n = 6) . | Day 14 (n = 6) . | Day 28 (n = 6) . |
---|---|---|---|
Hct (%) | 43.7 ± 0.8 | 43.4 ± 1.0 | 40 ± 2.2* |
Hb (g/dL) | 14.2 ± 0.6 | 13.6 ± 0.4 | 11.2 ± 1.2* |
MCHC (g/dL) | 30.4 ± 1.2 | 31.5 ± 0.8 | 32.0 ± 0.4† |
D50 | 1.090 ± 0.001 | 1.094 ± 0.001* | 1.094 ± 0.002* |
Reticulocytes (%) | 3.6 ± 0.4 | 6.1 ± 1.2* | 3.1 ± 0.4 |
Corrected reticulocyte count (%) | 3.6 ± 0.4 | 6.1 ± 1.2* | 2.84 ± 0.4 |
Serum Mg (mmol/L) | 2.7 ± 0.2 | 1.3 ± 0.1* | 1.4 ± 0.4* |
Erythrocyte Mg (mmol/kg Hb) | 9.2 ± 0.4 | 7.2 ± 0.1* | 7.9 ± 0.1* |
Cell Na (mmol/kg Hb) | 52.2 ± 2.1 | 55 ± 2.8 | 56.5 ± 2.4† |
Cell K (mmol/kg Hb) | 430 ± 17 | 324 ± 12* | 375 ± 22.3* |
Cell Na + K (mmol/kg Hb) | 483 ± 17.2 (6) | 379 ± 12 (6)* | 431 ± 20 (6)* |
K-Cl cotransport (mmol/L cells⋅h) | 4.2 ± 0.5 | 5.7 ± 0.8* | 5.6 ± 1.3* |
Data are presented as the mean ± SD.
P < .005, † P < .05: v baseline.