Table 1.

Hematologic Data in C57BL/6 Controls and β Thal Mice Maintained on a Standard-Mg Diet

ParameterC57BL/6β thal
Hct (%) 45.2 ± 0.5 32.1 ± 1.3* 
Hb (g/dL) 14.3 ± 0.4 9.90 ± 0.3* 
MCHC (g/dL) 29.1 ± 0.5 32.2 ± 0.8* 
D50 1.090 ± 0.001 1.101 ± 0.001* 
Reticulocytes (%) 3.2 ± 0.2 28.6 ± 2.1* 
Corrected reticulocyte count (%) 2.3 ± 0.2 20.3 ± 1.5* 
Serum Mg (mmol/L) 2.7 ± 0.3 1.9 ± 0.2* 
Cell Mg (mmol/kg Hb) 9.05 ± 0.2 8.9 ± 0.3 
Cell Na (mmol/kg Hb) 52.6 ± 2.7 51.5 ± 1.8 
Cell K (mmol/kg Hb) 423.3 ± 19.5 287.4 ± 12.1* 
Cell Na + K (mmol/kg Hb)  472 ± 16 336.5 ± 7.4* 
ParameterC57BL/6β thal
Hct (%) 45.2 ± 0.5 32.1 ± 1.3* 
Hb (g/dL) 14.3 ± 0.4 9.90 ± 0.3* 
MCHC (g/dL) 29.1 ± 0.5 32.2 ± 0.8* 
D50 1.090 ± 0.001 1.101 ± 0.001* 
Reticulocytes (%) 3.2 ± 0.2 28.6 ± 2.1* 
Corrected reticulocyte count (%) 2.3 ± 0.2 20.3 ± 1.5* 
Serum Mg (mmol/L) 2.7 ± 0.3 1.9 ± 0.2* 
Cell Mg (mmol/kg Hb) 9.05 ± 0.2 8.9 ± 0.3 
Cell Na (mmol/kg Hb) 52.6 ± 2.7 51.5 ± 1.8 
Cell K (mmol/kg Hb) 423.3 ± 19.5 287.4 ± 12.1* 
Cell Na + K (mmol/kg Hb)  472 ± 16 336.5 ± 7.4* 

Data are presented as the mean ± SD; n = 18 for both C57BL/6 and β thal groups. Corrected reticulocyte count based on baseline 45.2% Hct of C57BL/6 controls.

*

P < .005 v control mouse group.

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