Hematologic Data in C57BL/6 Controls and β Thal Mice Maintained on a Standard-Mg Diet
Parameter . | C57BL/6 . | β thal . |
---|---|---|
Hct (%) | 45.2 ± 0.5 | 32.1 ± 1.3* |
Hb (g/dL) | 14.3 ± 0.4 | 9.90 ± 0.3* |
MCHC (g/dL) | 29.1 ± 0.5 | 32.2 ± 0.8* |
D50 | 1.090 ± 0.001 | 1.101 ± 0.001* |
Reticulocytes (%) | 3.2 ± 0.2 | 28.6 ± 2.1* |
Corrected reticulocyte count (%) | 2.3 ± 0.2 | 20.3 ± 1.5* |
Serum Mg (mmol/L) | 2.7 ± 0.3 | 1.9 ± 0.2* |
Cell Mg (mmol/kg Hb) | 9.05 ± 0.2 | 8.9 ± 0.3 |
Cell Na (mmol/kg Hb) | 52.6 ± 2.7 | 51.5 ± 1.8 |
Cell K (mmol/kg Hb) | 423.3 ± 19.5 | 287.4 ± 12.1* |
Cell Na + K (mmol/kg Hb) | 472 ± 16 | 336.5 ± 7.4* |
Parameter . | C57BL/6 . | β thal . |
---|---|---|
Hct (%) | 45.2 ± 0.5 | 32.1 ± 1.3* |
Hb (g/dL) | 14.3 ± 0.4 | 9.90 ± 0.3* |
MCHC (g/dL) | 29.1 ± 0.5 | 32.2 ± 0.8* |
D50 | 1.090 ± 0.001 | 1.101 ± 0.001* |
Reticulocytes (%) | 3.2 ± 0.2 | 28.6 ± 2.1* |
Corrected reticulocyte count (%) | 2.3 ± 0.2 | 20.3 ± 1.5* |
Serum Mg (mmol/L) | 2.7 ± 0.3 | 1.9 ± 0.2* |
Cell Mg (mmol/kg Hb) | 9.05 ± 0.2 | 8.9 ± 0.3 |
Cell Na (mmol/kg Hb) | 52.6 ± 2.7 | 51.5 ± 1.8 |
Cell K (mmol/kg Hb) | 423.3 ± 19.5 | 287.4 ± 12.1* |
Cell Na + K (mmol/kg Hb) | 472 ± 16 | 336.5 ± 7.4* |
Data are presented as the mean ± SD; n = 18 for both C57BL/6 and β thal groups. Corrected reticulocyte count based on baseline 45.2% Hct of C57BL/6 controls.
P < .005 v control mouse group.