Spleen Colony Formation of Nonadherent Cells Produced by LTBMCs
| Examined Time (wk) . | No. Total Colonies . | Rad Cont . | |
|---|---|---|---|
| Control . | TN-C DM . | ||
| 7-wk-old mice | |||
| 0 | 38 ± 1 | 21 ± 2* | 0 ± 0 |
| 4 | 16 ± 2 | 9 ± 2† | 0 ± 0 |
| 8 | 7 ± 1 | 3 ± 1 | 0 ± 0 |
| 12 | 6 ± 1 | 4 ± 1* | 0 ± 0 |
| 50-wk-old mice | |||
| 0 | 26 ± 2 | 15 ± 2* | 0 ± 0 |
| 4 | 16 ± 2 | 12 ± 1 | 0 ± 0 |
| 8 | 7 ± 1 | 3 ± 1† | 0 ± 0 |
| Examined Time (wk) . | No. Total Colonies . | Rad Cont . | |
|---|---|---|---|
| Control . | TN-C DM . | ||
| 7-wk-old mice | |||
| 0 | 38 ± 1 | 21 ± 2* | 0 ± 0 |
| 4 | 16 ± 2 | 9 ± 2† | 0 ± 0 |
| 8 | 7 ± 1 | 3 ± 1 | 0 ± 0 |
| 12 | 6 ± 1 | 4 ± 1* | 0 ± 0 |
| 50-wk-old mice | |||
| 0 | 26 ± 2 | 15 ± 2* | 0 ± 0 |
| 4 | 16 ± 2 | 12 ± 1 | 0 ± 0 |
| 8 | 7 ± 1 | 3 ± 1† | 0 ± 0 |
Spleen colonies were counted at day 12. Data represented as mean colony number ± SD per 5 × 105 nonadherent cells. Five mice were used in each group.
Abbreviations: TN-C DM, tenascin-C–deficient mutant mice; Rad Cont, irradiated control mice without cell inoculation.
P < .01, †P < .05, according to Student'st-test.