Table 2.

Determination of FasL Expression (MFI) in Lymphocytic Subsets of B-CLL Patients and Healthy Individuals

Lymphocytic Subset B-CLL Patients PHealthy Donors
CD4+ 4.2 ± .63  <.009 2.1 ± .5  
CD8+ 2.8 ± .29  >.2 2.0 ± .7  
CD19+ 2.4 ± .21  >.9 2.3 ± .1 
Lymphocytic Subset B-CLL Patients PHealthy Donors
CD4+ 4.2 ± .63  <.009 2.1 ± .5  
CD8+ 2.8 ± .29  >.2 2.0 ± .7  
CD19+ 2.4 ± .21  >.9 2.3 ± .1 

MFI was determined by immunofluorescence staining and FACS analysis and calculated as the ratio of the MFI achieved with anti FasL MoAb/isotype control Moab. MFI >1.5 was considered positive. Means ± SEM of 30 B-CLL patients and 20 healthy individuals are given.

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