Bronchoalveolar Lavage Findings in 12 Patients With HIV Infection and T-Cell Alveolitis
Patients . | Cell Recovery . | Lymphocytes . | Alveolar Macrophages . | Neutrophils . | Eosinophils . | CD3 T Cells . | CD4 T Cells . | CD8 T Cells . | |||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
. | ×103 . | % . | ×103 . | % . | ×103 . | % . | ×103 . | % . | ×103 . | % . | ×103 . | % . | ×103 . | % . | ×103 . |
1 (ARC) | 297 | 35 | 103.9 | 65 | 193.1 | 0 | 0 | 0 | 0 | 89 | 91.6 | 1 | 1.0 | 88 | 90.6 |
2 (ARC) | 367 | 41 | 147.6 | 58 | 212.9 | 1 | 3.6 | 0 | 0 | 91 | 133.7 | 1 | 1.4 | 88 | 129.4 |
3 (AIDS) | 263 | 32 | 84.2 | 63 | 165.6 | 3 | 7.8 | 1 | 2.6 | 90 | 75.6 | 0.5 | 0.4 | 89 | 74.1 |
4 (AIDS) | 389 | 40 | 155.6 | 60 | 233.4 | 0 | 0 | 0 | 0 | 93 | 144.1 | 1 | 1.5 | 92 | 142.6 |
5 (AIDS) | 350 | 36 | 115.6 | 63 | 220.5 | 1 | 3.5 | 0 | 0 | 95 | 109.2 | 0.5 | 0.5 | 94 | 108.6 |
6 (AIDS) | 307 | 33 | 101.3 | 65 | 199.5 | 2 | 6.0 | 0 | 0 | 90 | 90.9 | 1 | 1.0 | 90 | 90.9 |
7 (AIDS) | 945 | 20 | 189.0 | 75 | 708.7 | 5 | 47.2 | 0 | 0 | 90 | 170.1 | 0.5 | 0.9 | 90 | 170.1 |
8 (AIDS) | 800 | 42 | 336.0 | 56 | 448.0 | 1 | 8.0 | 1 | 9.0 | 96 | 322.5 | 1 | 3.6 | 93 | 312.4 |
9 (AIDS) | 289 | 38 | 76.8 | 61 | 176.3 | 0 | 0 | 1 | 0.3 | 89 | 68.3 | 1 | 0.7 | 88 | 66.8 |
10 (AIDS) | 333 | 25 | 82.1 | 70 | 231.1 | 4 | 12.0 | 1 | 3.3 | 92 | 75.4 | 0.5 | 0.4 | 91 | 74.6 |
11 (AIDS) | 411 | 31 | 127.4 | 68 | 279.8 | 1 | 4.0 | 1 | 4.0 | 90 | 114.3 | 0.5 | 0.6 | 89 | 113.3 |
12 (AIDS) | 401 | 29 | 116.3 | 71 | 284.3 | 0 | 0 | 0 | 0 | 93 | 107.8 | 1 | 1.2 | 93 | 107.8 |
HIV infected patients (as a group) | 429.3 ± 214.3 | 33.5 ± 6.6 | 135.1 ± 70.9 | 64.5 ± 5.6 | 279.0 ± 154.4 | 1.5 ± 1.6 | 6.6 ± 13.0 | 0.3 ± 0.3 | 1.01 ± 2.6 | 91.4 ± 2.2 | 125.2 ± 68.9 | 0.79 ± 0.3 | 1.1 ± 0.9 | 90.4 ± 2.2 | 123.2 ± 66.7 |
Controls (n = 5) | 126.6 ± 16.4 | 6.8 ± 3.1 | 8.6 ± 3.4 | 90.8 ± 6.3 | 114.8 ± 18.8 | 0.2 ± 0.4 | 0.2 ± 0.4 | 0.1 ± 0.4 | 0.2 ± 0.2 | 87.8 ± 3.1 | 7.4 ± 2.9 | 57.6 ± 3.2 | 5.1 ± 1.9 | 30.4 ± 3.5 | 2.5 ± 1.0 |
P | .01 | .001 | .001 | .001 | NS | NS | NS | NS | NS | NS | .001 | .001 | .01 | .001 | .001 |
Patients . | Cell Recovery . | Lymphocytes . | Alveolar Macrophages . | Neutrophils . | Eosinophils . | CD3 T Cells . | CD4 T Cells . | CD8 T Cells . | |||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
. | ×103 . | % . | ×103 . | % . | ×103 . | % . | ×103 . | % . | ×103 . | % . | ×103 . | % . | ×103 . | % . | ×103 . |
1 (ARC) | 297 | 35 | 103.9 | 65 | 193.1 | 0 | 0 | 0 | 0 | 89 | 91.6 | 1 | 1.0 | 88 | 90.6 |
2 (ARC) | 367 | 41 | 147.6 | 58 | 212.9 | 1 | 3.6 | 0 | 0 | 91 | 133.7 | 1 | 1.4 | 88 | 129.4 |
3 (AIDS) | 263 | 32 | 84.2 | 63 | 165.6 | 3 | 7.8 | 1 | 2.6 | 90 | 75.6 | 0.5 | 0.4 | 89 | 74.1 |
4 (AIDS) | 389 | 40 | 155.6 | 60 | 233.4 | 0 | 0 | 0 | 0 | 93 | 144.1 | 1 | 1.5 | 92 | 142.6 |
5 (AIDS) | 350 | 36 | 115.6 | 63 | 220.5 | 1 | 3.5 | 0 | 0 | 95 | 109.2 | 0.5 | 0.5 | 94 | 108.6 |
6 (AIDS) | 307 | 33 | 101.3 | 65 | 199.5 | 2 | 6.0 | 0 | 0 | 90 | 90.9 | 1 | 1.0 | 90 | 90.9 |
7 (AIDS) | 945 | 20 | 189.0 | 75 | 708.7 | 5 | 47.2 | 0 | 0 | 90 | 170.1 | 0.5 | 0.9 | 90 | 170.1 |
8 (AIDS) | 800 | 42 | 336.0 | 56 | 448.0 | 1 | 8.0 | 1 | 9.0 | 96 | 322.5 | 1 | 3.6 | 93 | 312.4 |
9 (AIDS) | 289 | 38 | 76.8 | 61 | 176.3 | 0 | 0 | 1 | 0.3 | 89 | 68.3 | 1 | 0.7 | 88 | 66.8 |
10 (AIDS) | 333 | 25 | 82.1 | 70 | 231.1 | 4 | 12.0 | 1 | 3.3 | 92 | 75.4 | 0.5 | 0.4 | 91 | 74.6 |
11 (AIDS) | 411 | 31 | 127.4 | 68 | 279.8 | 1 | 4.0 | 1 | 4.0 | 90 | 114.3 | 0.5 | 0.6 | 89 | 113.3 |
12 (AIDS) | 401 | 29 | 116.3 | 71 | 284.3 | 0 | 0 | 0 | 0 | 93 | 107.8 | 1 | 1.2 | 93 | 107.8 |
HIV infected patients (as a group) | 429.3 ± 214.3 | 33.5 ± 6.6 | 135.1 ± 70.9 | 64.5 ± 5.6 | 279.0 ± 154.4 | 1.5 ± 1.6 | 6.6 ± 13.0 | 0.3 ± 0.3 | 1.01 ± 2.6 | 91.4 ± 2.2 | 125.2 ± 68.9 | 0.79 ± 0.3 | 1.1 ± 0.9 | 90.4 ± 2.2 | 123.2 ± 66.7 |
Controls (n = 5) | 126.6 ± 16.4 | 6.8 ± 3.1 | 8.6 ± 3.4 | 90.8 ± 6.3 | 114.8 ± 18.8 | 0.2 ± 0.4 | 0.2 ± 0.4 | 0.1 ± 0.4 | 0.2 ± 0.2 | 87.8 ± 3.1 | 7.4 ± 2.9 | 57.6 ± 3.2 | 5.1 ± 1.9 | 30.4 ± 3.5 | 2.5 ± 1.0 |
P | .01 | .001 | .001 | .001 | NS | NS | NS | NS | NS | NS | .001 | .001 | .01 | .001 | .001 |
Abbreviation: NS, not significant.