Chemokine Receptors
| Receptor . | Ligands . |
|---|---|
| CXC Receptors | |
| CXCR1 | IL-8 |
| CXCR2 | IL-8, GRO-α, GRO-β, GRO-γ, NAP-2, ENA-78 |
| CXCR3 | IP-10, MIG |
| CXCR4 | SDF-1α |
| CC Receptors | |
| CCR1 | MIP-1α, RANTES, MCP-3 |
| CCR2 | MCP-1, MCP-3, MCP-5 |
| CCR3 | Eoxtaxin, RANTES, MCP-2, MCP-3, ?MCP-4 |
| CCR4 | MIP-1α, RANTES, MCP-1, TARC |
| CCR5 | MIP-1α, MIP-1β, RANTES |
| CCR6 | MIP-3α/LARC |
| CCR7 | MIP-3β/ELC |
| Receptor . | Ligands . |
|---|---|
| CXC Receptors | |
| CXCR1 | IL-8 |
| CXCR2 | IL-8, GRO-α, GRO-β, GRO-γ, NAP-2, ENA-78 |
| CXCR3 | IP-10, MIG |
| CXCR4 | SDF-1α |
| CC Receptors | |
| CCR1 | MIP-1α, RANTES, MCP-3 |
| CCR2 | MCP-1, MCP-3, MCP-5 |
| CCR3 | Eoxtaxin, RANTES, MCP-2, MCP-3, ?MCP-4 |
| CCR4 | MIP-1α, RANTES, MCP-1, TARC |
| CCR5 | MIP-1α, MIP-1β, RANTES |
| CCR6 | MIP-3α/LARC |
| CCR7 | MIP-3β/ELC |
Ligand assignments are based on in vitro binding assays showing Kd < 10 nmol/L. See text and “Note Added in Proof” for references.