Table 1.

CXC Chemokines

NameTarget Cells
ELR 
IL-8 Neutrophils, T lymphocytes, basophils, angiogenesis (?endothelial cells) 
GRO-α(MGSA) Neutrophils, melanoma cells, (?endothelial cells) 
GRO-β(MIP-2α) Neutrophils, (?endothelial cells) 
GRO-γ(MIP-2β) Neutrophils, (?endothelial cells) 
ENA-78 Neutrophils 
GCP-2 Neutrophils 
Platelet basic protein 
CTAP-III Fibroblasts 
β-Thromboglobulin Fibroblasts 
NAP-2 Neutrophils, basophils 
non-ELR 
Platelet factor 4 Fibroblasts, endothelial cells 
IP-10 Activated T lymphocytes, TIL, ?endothelial cells, ?NK cells 
MIG Activated T lymphocytes, TIL 
SDF-1α T lymphocytes, CD34+ progenitors, ?B lymphocytes 
SDF-1β 
NameTarget Cells
ELR 
IL-8 Neutrophils, T lymphocytes, basophils, angiogenesis (?endothelial cells) 
GRO-α(MGSA) Neutrophils, melanoma cells, (?endothelial cells) 
GRO-β(MIP-2α) Neutrophils, (?endothelial cells) 
GRO-γ(MIP-2β) Neutrophils, (?endothelial cells) 
ENA-78 Neutrophils 
GCP-2 Neutrophils 
Platelet basic protein 
CTAP-III Fibroblasts 
β-Thromboglobulin Fibroblasts 
NAP-2 Neutrophils, basophils 
non-ELR 
Platelet factor 4 Fibroblasts, endothelial cells 
IP-10 Activated T lymphocytes, TIL, ?endothelial cells, ?NK cells 
MIG Activated T lymphocytes, TIL 
SDF-1α T lymphocytes, CD34+ progenitors, ?B lymphocytes 
SDF-1β 

See text for references.

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