Table 1.

Reasons, Other Than Age, for the Exclusion From Entering the AIDA Protocol in 21 Patients Registered as AML-FAB M3

Exclusion CriteriaNo. of Cases
Karyotype NA*/PML-RARα-negative 
Karyotype NA/PML-RARα NE 
Karyotype NE‡/PML-RARα-negative 
Absence of t(15; 17)/PML-RARα-negative 
Absence of t(15; 17)/PML-RARα NE 
Karyotype NA/specimen for RT-PCR not sent 
t(11; 17)/PML-RARα-negative 
HIV-positive 
Poor performance status/active serious infection 
Other concomitant malignancy 
Exclusion CriteriaNo. of Cases
Karyotype NA*/PML-RARα-negative 
Karyotype NA/PML-RARα NE 
Karyotype NE‡/PML-RARα-negative 
Absence of t(15; 17)/PML-RARα-negative 
Absence of t(15; 17)/PML-RARα NE 
Karyotype NA/specimen for RT-PCR not sent 
t(11; 17)/PML-RARα-negative 
HIV-positive 
Poor performance status/active serious infection 
Other concomitant malignancy 

Abbreviations: NA, not available; HIV, human immunodeficiency virus.

*

Karyotype, not available.

PML-RARα NE, poor quality RNA.

Karyotype NE, no mitosis or poor quality metaphases.

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