CFU Assay (Day 14)
| . | Patient No. 4 . | Normal Values3-150 . | ||||
|---|---|---|---|---|---|---|
| . | CFU-GM . | BFU-E . | CFU-Mega . | Median (range) . | ||
| . | . | . | . | CFU-GM . | BFU-E . | CFU-Mega . |
| Control | 0 | 0 | 0 | 0 (0-3) | 0 (0-2) | 0 (0) |
| TPO3-151 | 2 | 0 | 0 | 0 (0-1) | 0 (0-3) | 11 (4-40) |
| G-CSF,† GM-CSF,† IL-3,† SCF,† EPO3-151 | 428 | 507 | nd3-152 | 125 (68-240) | 180 (91-431) | nd3-152 |
| . | Patient No. 4 . | Normal Values3-150 . | ||||
|---|---|---|---|---|---|---|
| . | CFU-GM . | BFU-E . | CFU-Mega . | Median (range) . | ||
| . | . | . | . | CFU-GM . | BFU-E . | CFU-Mega . |
| Control | 0 | 0 | 0 | 0 (0-3) | 0 (0-2) | 0 (0) |
| TPO3-151 | 2 | 0 | 0 | 0 (0-1) | 0 (0-3) | 11 (4-40) |
| G-CSF,† GM-CSF,† IL-3,† SCF,† EPO3-151 | 428 | 507 | nd3-152 | 125 (68-240) | 180 (91-431) | nd3-152 |
Colony numbers are based upon 105 BM-MNC. Data represent the mean of duplicates.
Obtained in our laboratory from 12 healthy individuals, using the same experimental conditions.
10 ng/mL each, except for EPO (1 U/mL).
Counting Mega-colonies was not possible in dishes with “maximum stimulation” because of the high numbers of colonies.