Presenting Features of Children With TL According to Myeloid Antigen Expression
| Variable . | Category . | My+ TL (N = 43) . | My− TL (N = 184) . | P Value3-150 . | ||
|---|---|---|---|---|---|---|
| . | . | No. . | (%) . | No. . | (%) . | . |
| Age (yr) | <1 | 1 | (2.3) | 1 | (0.5) | .003 |
| 1-9 | 18 | (41.9) | 126 | (68.5) | ||
| ≥10 | 24 | (55.8) | 57 | (31.0) | ||
| WBC (×109/L) | 1-19 | 13 | (30.2) | 51 | (27.7) | .93 |
| 20-49 | 5 | (11.6) | 24 | (13.0) | ||
| ≥50 | 25 | (58.1) | 109 | (59.2) | ||
| Sex | Male | 34 | (79.1) | 133 | (72.3) | .47 |
| Female | 9 | (20.9) | 51 | (27.7) | ||
| Race | White | 29 | (67.4) | 135 | (73.8) | .54 |
| Black | 7 | (16.3) | 19 | (10.4) | ||
| Other | 7 | (16.3) | 29 | (15.8) | ||
| Down syndrome | Yes | 0 | (0.0) | 3 | (1.6) | .92 |
| No | 43 | (100.0) | 180 | (98.4) | ||
| Liver | Normal | 28 | (65.1) | 54 | (29.8) | .12 |
| Mod. enlarged3-151 | 13 | (30.2) | 108 | (59.7) | ||
| Markedly enlarged | 2 | (4.7) | 19 | (10.5) | ||
| Spleen | Normal | 21 | (48.8) | 155 | (29.9) | .06 |
| Mod. enlarged | 16 | (37.2) | 93 | (50.5) | ||
| Markedly enlarged | 6 | (14.0) | 36 | (19.6) | ||
| Lymph nodes | Normal | 18 | (41.9) | 44 | (23.9) | .05 |
| Mod. enlarged | 15 | (34.9) | 76 | (41.3) | ||
| Markedly enlarged | 10 | (23.3) | 64 | (34.8) | ||
| Mediastinal mass | Absent | 29 | (67.4) | 77 | (41.8) | .008 |
| Small | 5 | (11.6) | 26 | (14.1) | ||
| Large | 9 | (20.9) | 81 | (44.0) | ||
| Hemoglobin (g/dL) | 1-7.9 | 12 | (27.9) | 50 | (27.8) | .02 |
| 8.0.-10.9 | 22 | (51.2) | 56 | (31.1) | ||
| ≥11.0 | 9 | (20.9) | 74 | (41.1) | ||
| Platelets (×109/L) | 1-49 | 10 | (23.3) | 74 | (40.4) | .11 |
| 50-149 | 19 | (44.2) | 63 | (34.4) | ||
| ≥150 | 14 | (32.6) | 46 | (25.1) | ||
| CNS disease at diagnosis | Yes | 3 | (7.0) | 16 | (8.8) | .93 |
| No | 40 | (93.0) | 165 | (91.2) | ||
| Karyotypic features | ||||||
| Number | Diploid (46) | 8 | (47.1) | 36 | (43.9) | .96 |
| Hypodiploid (<46) | 0 | (0.0) | 2 | (2.4) | ||
| Pseudodiploid (46) | 7 | (41.2) | 33 | (40.2) | ||
| Hyperdiploid (47-50) | 2 | (11.8) | 10 | (12.2) | ||
| Hyperdiploid (>50) | 0 | (0.0) | 1 | (1.2) | ||
| Aberrations | Normal | 8 | (47.1) | 36 | (43.9) | .98 |
| Abnormal | 9 | (52.9) | 46 | (56.1) | ||
| Variable . | Category . | My+ TL (N = 43) . | My− TL (N = 184) . | P Value3-150 . | ||
|---|---|---|---|---|---|---|
| . | . | No. . | (%) . | No. . | (%) . | . |
| Age (yr) | <1 | 1 | (2.3) | 1 | (0.5) | .003 |
| 1-9 | 18 | (41.9) | 126 | (68.5) | ||
| ≥10 | 24 | (55.8) | 57 | (31.0) | ||
| WBC (×109/L) | 1-19 | 13 | (30.2) | 51 | (27.7) | .93 |
| 20-49 | 5 | (11.6) | 24 | (13.0) | ||
| ≥50 | 25 | (58.1) | 109 | (59.2) | ||
| Sex | Male | 34 | (79.1) | 133 | (72.3) | .47 |
| Female | 9 | (20.9) | 51 | (27.7) | ||
| Race | White | 29 | (67.4) | 135 | (73.8) | .54 |
| Black | 7 | (16.3) | 19 | (10.4) | ||
| Other | 7 | (16.3) | 29 | (15.8) | ||
| Down syndrome | Yes | 0 | (0.0) | 3 | (1.6) | .92 |
| No | 43 | (100.0) | 180 | (98.4) | ||
| Liver | Normal | 28 | (65.1) | 54 | (29.8) | .12 |
| Mod. enlarged3-151 | 13 | (30.2) | 108 | (59.7) | ||
| Markedly enlarged | 2 | (4.7) | 19 | (10.5) | ||
| Spleen | Normal | 21 | (48.8) | 155 | (29.9) | .06 |
| Mod. enlarged | 16 | (37.2) | 93 | (50.5) | ||
| Markedly enlarged | 6 | (14.0) | 36 | (19.6) | ||
| Lymph nodes | Normal | 18 | (41.9) | 44 | (23.9) | .05 |
| Mod. enlarged | 15 | (34.9) | 76 | (41.3) | ||
| Markedly enlarged | 10 | (23.3) | 64 | (34.8) | ||
| Mediastinal mass | Absent | 29 | (67.4) | 77 | (41.8) | .008 |
| Small | 5 | (11.6) | 26 | (14.1) | ||
| Large | 9 | (20.9) | 81 | (44.0) | ||
| Hemoglobin (g/dL) | 1-7.9 | 12 | (27.9) | 50 | (27.8) | .02 |
| 8.0.-10.9 | 22 | (51.2) | 56 | (31.1) | ||
| ≥11.0 | 9 | (20.9) | 74 | (41.1) | ||
| Platelets (×109/L) | 1-49 | 10 | (23.3) | 74 | (40.4) | .11 |
| 50-149 | 19 | (44.2) | 63 | (34.4) | ||
| ≥150 | 14 | (32.6) | 46 | (25.1) | ||
| CNS disease at diagnosis | Yes | 3 | (7.0) | 16 | (8.8) | .93 |
| No | 40 | (93.0) | 165 | (91.2) | ||
| Karyotypic features | ||||||
| Number | Diploid (46) | 8 | (47.1) | 36 | (43.9) | .96 |
| Hypodiploid (<46) | 0 | (0.0) | 2 | (2.4) | ||
| Pseudodiploid (46) | 7 | (41.2) | 33 | (40.2) | ||
| Hyperdiploid (47-50) | 2 | (11.8) | 10 | (12.2) | ||
| Hyperdiploid (>50) | 0 | (0.0) | 1 | (1.2) | ||
| Aberrations | Normal | 8 | (47.1) | 36 | (43.9) | .98 |
| Abnormal | 9 | (52.9) | 46 | (56.1) | ||