In Vitro Effects of As2O3 on Cells From Patients With B-CLL
| Patient No. . | Day . | Mean Viability (%) . | ||||
|---|---|---|---|---|---|---|
| . | . | Control . | As2O3 10−6 mol/L . | As2O310−7 mol/L . | As2O310−8 mol/L . | As2O310−9 mol/L . |
| P1 | 1 | 87 ± 1 | ND | 91 ± 3 | 90 ± 4 | 89 ± 4 |
| 2 | 82 ± 5 | ND | 82 ± 1 | 83 ± 3 | 92 ± 4 | |
| 3 | 81 ± 4 | ND | 67 ± 2 | 74 ± 7 | 85 ± 8 | |
| 4 | 86 ± 3 | ND | 78 ± 4 | 84 ± 1 | 90 ± 4 | |
| P2 | 1 | ND | ND | ND | ND | ND |
| 2 | ND | ND | ND | ND | ND | |
| 3 | ND | ND | ND | ND | ND | |
| 4 | ND | ND | ND | ND | ND | |
| P3 | 1 | ND | ND | ND | ND | ND |
| 2 | ND | ND | ND | ND | ND | |
| 3 | ND | ND | ND | ND | ND | |
| 4 | ND | ND | ND | ND | ND | |
| P4 | 1 | 86 ± 1 | 87 ± 7 | 87 ± 8 | 88 ± 4 | 96 ± 6 |
| 2 | 89 ± 1 | 84 ± 5 | 87 ± 4 | 91 ± 8 | 91 ± 8 | |
| 3 | 83 ± 2 | 73 ± 5 | 76 ± 10 | 76 ± 8 | 84 ± 3 | |
| 4 | 80 ± 7 | 48 ± 9 | 72 ± 6 | 72 ± 11 | 71 ± 4 | |
| P5 | 1 | 81 ± 9 | 86 ± 6 | 85 ± 2 | 92 ± 7 | 88 ± 3 |
| 2 | 91 ± 0 | 92 ± 2 | 82 ± 16 | 86 ± 5 | 93 ± 2 | |
| 3 | 94 ± 3 | 93 ± 6 | 86 ± 8 | 94 ± 5 | 96 ± 7 | |
| 4 | 89 ± 7 | 92 ± 4 | 92 ± 3 | 91 ± 5 | 94 ± 2 | |
| Patient No. . | Day . | Mean Viability (%) . | ||||
|---|---|---|---|---|---|---|
| . | . | Control . | As2O3 10−6 mol/L . | As2O310−7 mol/L . | As2O310−8 mol/L . | As2O310−9 mol/L . |
| P1 | 1 | 87 ± 1 | ND | 91 ± 3 | 90 ± 4 | 89 ± 4 |
| 2 | 82 ± 5 | ND | 82 ± 1 | 83 ± 3 | 92 ± 4 | |
| 3 | 81 ± 4 | ND | 67 ± 2 | 74 ± 7 | 85 ± 8 | |
| 4 | 86 ± 3 | ND | 78 ± 4 | 84 ± 1 | 90 ± 4 | |
| P2 | 1 | ND | ND | ND | ND | ND |
| 2 | ND | ND | ND | ND | ND | |
| 3 | ND | ND | ND | ND | ND | |
| 4 | ND | ND | ND | ND | ND | |
| P3 | 1 | ND | ND | ND | ND | ND |
| 2 | ND | ND | ND | ND | ND | |
| 3 | ND | ND | ND | ND | ND | |
| 4 | ND | ND | ND | ND | ND | |
| P4 | 1 | 86 ± 1 | 87 ± 7 | 87 ± 8 | 88 ± 4 | 96 ± 6 |
| 2 | 89 ± 1 | 84 ± 5 | 87 ± 4 | 91 ± 8 | 91 ± 8 | |
| 3 | 83 ± 2 | 73 ± 5 | 76 ± 10 | 76 ± 8 | 84 ± 3 | |
| 4 | 80 ± 7 | 48 ± 9 | 72 ± 6 | 72 ± 11 | 71 ± 4 | |
| P5 | 1 | 81 ± 9 | 86 ± 6 | 85 ± 2 | 92 ± 7 | 88 ± 3 |
| 2 | 91 ± 0 | 92 ± 2 | 82 ± 16 | 86 ± 5 | 93 ± 2 | |
| 3 | 94 ± 3 | 93 ± 6 | 86 ± 8 | 94 ± 5 | 96 ± 7 | |
| 4 | 89 ± 7 | 92 ± 4 | 92 ± 3 | 91 ± 5 | 94 ± 2 | |
Numbers represent the mean and standard deviation evaluated in triplicate.
Abbreviation: ND, not done.