Generation of Autologous Antileukemia T-Cell Lines From the Peripheral Blood of Patients With Pre-B–Cell Leukemias: Comparison With Bone Marrow
| Patient . | Peripheral Blood . | ||||||
|---|---|---|---|---|---|---|---|
| . | Day 0 (T-cell number) . | Day 30 (T-cell expansion) . | Bone Marrow . | . | |||
| . | CD4+ . | CD8+ . | CD4+ . | CD8+ . | Day 30 (T-cell expansion) . | CD8+ . | . |
| . | . | . | . | . | CD4+ . | . | . |
| ALL-17 | 5.0 × 106 | 1.7 × 106 | 0 | 0 | 22.5 | 70.0 | |
| ALL-20 | 7.1 × 106 | 4.4 × 106 | 0 | 0 | 28.9 | 68.3 | |
| ALL-30 | 3.2 × 106 | 2.0 × 106 | 0 | 0 | 0 | 0 | |
| ALL-31 | 1.1 × 106 | 0.8 × 106 | 0 | 0 | 7.1 | 15.8 | |
| ALL-36 | 3.7 × 106 | 2.1 × 106 | 0 | 0 | 0 | 0 | |
| ALL-41 | 4.3 × 106 | 3.5 × 106 | 0 | 0 | 12.1 | 48.8 | |
| CML-1 | 4.6 × 106 | 1.9 × 106 | 0 | 0 | 7.0 | 5.7 | |
| Patient . | Peripheral Blood . | ||||||
|---|---|---|---|---|---|---|---|
| . | Day 0 (T-cell number) . | Day 30 (T-cell expansion) . | Bone Marrow . | . | |||
| . | CD4+ . | CD8+ . | CD4+ . | CD8+ . | Day 30 (T-cell expansion) . | CD8+ . | . |
| . | . | . | . | . | CD4+ . | . | . |
| ALL-17 | 5.0 × 106 | 1.7 × 106 | 0 | 0 | 22.5 | 70.0 | |
| ALL-20 | 7.1 × 106 | 4.4 × 106 | 0 | 0 | 28.9 | 68.3 | |
| ALL-30 | 3.2 × 106 | 2.0 × 106 | 0 | 0 | 0 | 0 | |
| ALL-31 | 1.1 × 106 | 0.8 × 106 | 0 | 0 | 7.1 | 15.8 | |
| ALL-36 | 3.7 × 106 | 2.1 × 106 | 0 | 0 | 0 | 0 | |
| ALL-41 | 4.3 × 106 | 3.5 × 106 | 0 | 0 | 12.1 | 48.8 | |
| CML-1 | 4.6 × 106 | 1.9 × 106 | 0 | 0 | 7.0 | 5.7 | |