Serum Iron/TIBC, Total Serum Iron, and MCH Following TBI
| Parameter . | Preirradiation . | Day 14 . | Day 28 . | Day 43 . |
|---|---|---|---|---|
| Serum iron/TIBC (%) | ||||
| TPO | 27 ± 12 | 35 ± 8‡ | 12 ± 7 | 6 ± 1†‡ |
| Placebo | 31 ± 13 | 62 ± 11† | 30 ± 19 | 17 ± 8 |
| Serum iron (μmol/L) | ||||
| TPO | 21 ± 8 | 28 ± 8‡ | 10 ± 5 | 5 ± 1†‡ |
| Placebo | 22 ± 8 | 41 ± 8† | 21 ± 13 | 11 ± 4 |
| Iron/TPO | 39* | 31 | 23 | 20 |
| MCH (amol) | ||||
| TPO | 1,508 ± 94 | 1,464 ± 141 | 1,427 ± 113 | 1,210 ± 255 |
| Placebo | 1,437 ± 61 | 1,393 ± 64 | 1,471 ± 67 | 1,456 ± 75 |
| Parameter . | Preirradiation . | Day 14 . | Day 28 . | Day 43 . |
|---|---|---|---|---|
| Serum iron/TIBC (%) | ||||
| TPO | 27 ± 12 | 35 ± 8‡ | 12 ± 7 | 6 ± 1†‡ |
| Placebo | 31 ± 13 | 62 ± 11† | 30 ± 19 | 17 ± 8 |
| Serum iron (μmol/L) | ||||
| TPO | 21 ± 8 | 28 ± 8‡ | 10 ± 5 | 5 ± 1†‡ |
| Placebo | 22 ± 8 | 41 ± 8† | 21 ± 13 | 11 ± 4 |
| Iron/TPO | 39* | 31 | 23 | 20 |
| MCH (amol) | ||||
| TPO | 1,508 ± 94 | 1,464 ± 141 | 1,427 ± 113 | 1,210 ± 255 |
| Placebo | 1,437 ± 61 | 1,393 ± 64 | 1,471 ± 67 | 1,456 ± 75 |
TPO-treated monkeys, n = 4; placebo-treated monkeys, n = 4; iron/TPO (monkey treated with iron before irradiation and TPO after irradiation), n = 1.
After iron supplementation.
Statistically significantly different from preirradiation, P < .05.
Statistically significantly different from time-matched placebo-treated monkeys, P < .05.