Table 2.

Genotypic — Phenotypic Correlations

GroupNMedian Age of HA* (yr) (95% CI)Mean No. CM†Est. Median Survival (yr) (95% CI)
Exon 1 17 7.60 (5.85-9.35) 0.6 19.65 (16.62-22.68) 
IVS4 26 2.72 (2.32-3.12) 3.7 14.87 (8.65-21.09) 
Exon 14 16 2.13 (1.69-2.57) 2.5 9.74 (6.89-12.59) 
Non-C 338 6.6 (6.17-7.03)  —  23.0 (19.27-26.73) 
GroupNMedian Age of HA* (yr) (95% CI)Mean No. CM†Est. Median Survival (yr) (95% CI)
Exon 1 17 7.60 (5.85-9.35) 0.6 19.65 (16.62-22.68) 
IVS4 26 2.72 (2.32-3.12) 3.7 14.87 (8.65-21.09) 
Exon 14 16 2.13 (1.69-2.57) 2.5 9.74 (6.89-12.59) 
Non-C 338 6.6 (6.17-7.03)  —  23.0 (19.27-26.73) 

Median ages of hematologic onset and survival were determined by Kaplan-Meier analysis.

*

Hematologic abnormality: platelets <100 × 109/L, Hgb <10 g/dL, or neutrophils <1 × 109/L.

†

Major congenital malformations.

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